The retinaldehyde reductase activity of DHRS3 is reciprocally activated by retinol dehydrogenase 10 to control retinoid homeostasis.

Adams, Mark K; Belyaeva, Olga V; Wu, Lizhi; Kedishvili, Natalia Y

Adams, Mark K; Belyaeva, Olga V; Wu, Lizhi; Kedishvili, Natalia Y.

Affiliation

Adams MK; From the Department of Biochemistry and Molecular Genetics, Schools of Medicine and Dentistry, University of Alabama at Birmingham, Birmingham, Alabama 35294.
Belyaeva OV; From the Department of Biochemistry and Molecular Genetics, Schools of Medicine and Dentistry, University of Alabama at Birmingham, Birmingham, Alabama 35294.
Wu L; From the Department of Biochemistry and Molecular Genetics, Schools of Medicine and Dentistry, University of Alabama at Birmingham, Birmingham, Alabama 35294.
Kedishvili NY; From the Department of Biochemistry and Molecular Genetics, Schools of Medicine and Dentistry, University of Alabama at Birmingham, Birmingham, Alabama 35294 nkedishvili@uab.edu.

J Biol Chem ; 289(21): 14868-80, 2014 May 23.

Article in En | MEDLINE | ID: mdl-24733397

Subject(s)

Alcohol Oxidoreductases/metabolism; Homeostasis; Retinaldehyde/metabolism; Alcohol Oxidoreductases/genetics; Animals; Biocatalysis; Blotting, Western; Cells, Cultured; Enzyme Activation; Female; HEK293 Cells; Hep G2 Cells; Humans; In Situ Hybridization; Limb Buds/embryology; Limb Buds/metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Protein Binding; RNA Interference; Reverse Transcriptase Polymerase Chain Reaction; Sf9 Cells; Vitamin A/metabolism

Key words

Dehydrogenase; Metabolism; Reductase; Retinoid; Vitamin A

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Full text: 1 Database: MEDLINE Main subject: Retinaldehyde / Alcohol Oxidoreductases / Homeostasis Limits: Animals / Female / Humans / Male Language: En Year: 2014 Type: Article

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