Mitochondrial and inflammatory changes in sporadic inclusion body myositis.

Rygiel, Karolina A; Miller, James; Grady, John P; Rocha, Mariana C; Taylor, Robert W; Turnbull, Doug M

Rygiel, Karolina A; Miller, James; Grady, John P; Rocha, Mariana C; Taylor, Robert W; Turnbull, Doug M.

Affiliation

Rygiel KA; Wellcome Trust Centre for Mitochondrial Research, Institute for Ageing and Health, The Medical School, Newcastle University, Newcastle upon Tyne, UK; Newcastle University Centre for Brain Ageing and Vitality, Institute for Ageing and Health, The Medical School, Newcastle University, Newcastle upon Tyne, UK.

Neuropathol Appl Neurobiol ; 41(3): 288-303, 2015 Apr.

Article in En | MEDLINE | ID: mdl-24750247

Subject(s)

Inflammation/pathology; Mitochondria/pathology; Myositis, Inclusion Body/pathology; DNA, Mitochondrial/genetics; Humans; Immunohistochemistry; Mutation; Real-Time Polymerase Chain Reaction

Key words

atrophy; complex I; inflammation; mitochondria; mitochondrial deletions; sIBM

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Full text: 1 Database: MEDLINE Main subject: Myositis, Inclusion Body / Inflammation / Mitochondria Type of study: Prognostic_studies Limits: Humans Language: En Year: 2015 Type: Article

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