Acute-phase protein &#945;1-antitrypsin--a novel regulator of angiopoietin-like protein 4 transcription and secretion.

Frenzel, Eileen; Wrenger, Sabine; Immenschuh, Stephan; Koczulla, Rembert; Mahadeva, Ravi; Deeg, H Joachim; Dinarello, Charles A; Welte, Tobias; Marcondes, A Mario Q; Janciauskiene, Sabina

Acute-phase protein α1-antitrypsin--a novel regulator of angiopoietin-like protein 4 transcription and secretion.

Frenzel, Eileen; Wrenger, Sabine; Immenschuh, Stephan; Koczulla, Rembert; Mahadeva, Ravi; Deeg, H Joachim; Dinarello, Charles A; Welte, Tobias; Marcondes, A Mario Q; Janciauskiene, Sabina.

Affiliation

Frenzel E; Department of Respiratory Medicine, Hannover Medical School, 30625 Hannover, Germany;
Wrenger S; Department of Respiratory Medicine, Hannover Medical School, 30625 Hannover, Germany;
Immenschuh S; Institute for Transfusion Medicine, Hannover Medical School, 30625 Hannover, Germany;
Koczulla R; Division of Pulmonary Diseases, Department of Internal Medicine, Philipps-Universität Marburg, 35037 Marburg, Germany;
Mahadeva R; Department of Respiratory Medicine, University of Cambridge, Cambridge CB2 0QQ, United Kingdom;
Deeg HJ; Department of Medicine, University of Washington, Seattle, WA 98195; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109; and.
Dinarello CA; Department of Medicine, University of Colorado Denver, Aurora, CO 80045.
Welte T; Department of Respiratory Medicine, Hannover Medical School, 30625 Hannover, Germany;
Marcondes AM; Department of Medicine, University of Washington, Seattle, WA 98195; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109; and.
Janciauskiene S; Department of Respiratory Medicine, Hannover Medical School, 30625 Hannover, Germany; janciauskiene.sabina@mh-hannover.de.

J Immunol ; 192(11): 5354-62, 2014 Jun 01.

Article in En | MEDLINE | ID: mdl-24760148

Subject(s)

Angiopoietins/immunology; Endothelial Cells/immunology; Gene Expression Regulation/immunology; Leukocytes, Mononuclear/immunology; Transcription, Genetic/immunology; alpha 1-Antitrypsin/immunology; Angiopoietin-Like Protein 1; Angiopoietin-like Proteins; Angiopoietins/metabolism; Anilides/pharmacology; Emphysema/drug therapy; Emphysema/immunology; Emphysema/pathology; Endothelial Cells/metabolism; Endothelial Cells/pathology; Female; Gene Expression Regulation/drug effects; Humans; Hypoxia-Inducible Factor 1, alpha Subunit/genetics; Hypoxia-Inducible Factor 1, alpha Subunit/immunology; Leukocytes, Mononuclear/metabolism; Leukocytes, Mononuclear/pathology; MAP Kinase Signaling System/drug effects; MAP Kinase Signaling System/immunology; Male; Mitogen-Activated Protein Kinase 1/immunology; Mitogen-Activated Protein Kinase 1/metabolism; Mitogen-Activated Protein Kinase 3/immunology; Mitogen-Activated Protein Kinase 3/metabolism; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphorylation/drug effects; Phosphorylation/immunology; Serine Proteinase Inhibitors/immunology; Serine Proteinase Inhibitors/pharmacology; Transcription Factors/immunology; Transcription Factors/metabolism; Transcription, Genetic/drug effects; alpha 1-Antitrypsin/metabolism; alpha 1-Antitrypsin/pharmacology

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Full text: 1 Database: MEDLINE Main subject: Transcription, Genetic / Leukocytes, Mononuclear / Alpha 1-Antitrypsin / Gene Expression Regulation / Endothelial Cells / Angiopoietins Language: En Year: 2014 Type: Article

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