Model-based cell number quantification using online single-oxygen sensor data for tissue engineering perfusion bioreactors.

Lambrechts, T; Papantoniou, I; Sonnaert, M; Schrooten, J; Aerts, J-M

Lambrechts, T; Papantoniou, I; Sonnaert, M; Schrooten, J; Aerts, J-M.

Affiliation

Lambrechts T; Division M3-BIORES: Measure, Model & Manage Bioresponses, KU Leuven, Heverlee, Belgium; Prometheus, Division of Skeletal Tissue Engineering, KU Leuven, Leuven, Belgium.

Biotechnol Bioeng ; 111(10): 1982-92, 2014 Oct.

Article in En | MEDLINE | ID: mdl-24771348

Subject(s)

Bioreactors; Biosensing Techniques/instrumentation; Oxygen/analysis; Oxygen/metabolism; Stem Cells/metabolism; Tissue Engineering/instrumentation; Cell Count; Cell Culture Techniques/instrumentation; Cells, Cultured; Equipment Design; Humans; Models, Biological; Perfusion/instrumentation; Stem Cells/cytology; Tissue Scaffolds/chemistry

Key words

bioprocess control; data-based mechanistic modeling; online monitoring; oxygen sensor; stem cell bioreactor; tissue engineering

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Full text: 1 Database: MEDLINE Main subject: Oxygen / Stem Cells / Biosensing Techniques / Bioreactors / Tissue Engineering Limits: Humans Language: En Year: 2014 Type: Article

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