EphrinB1 interacts with CNK1 and promotes cell migration through c-Jun N-terminal kinase (JNK) activation.

Cho, Hee Jun; Hwang, Yoo-Seok; Mood, Kathleen; Ji, Yon Ju; Lim, Junghwa; Morrison, Deborah K; Daar, Ira O

Cho, Hee Jun; Hwang, Yoo-Seok; Mood, Kathleen; Ji, Yon Ju; Lim, Junghwa; Morrison, Deborah K; Daar, Ira O.

Affiliation

Cho HJ; From the Laboratory of Cell and Developmental Signaling, National Cancer Institute-Frederick, National Institutes of Health, Frederick, Maryland 21702.
Hwang YS; From the Laboratory of Cell and Developmental Signaling, National Cancer Institute-Frederick, National Institutes of Health, Frederick, Maryland 21702.
Mood K; From the Laboratory of Cell and Developmental Signaling, National Cancer Institute-Frederick, National Institutes of Health, Frederick, Maryland 21702.
Ji YJ; From the Laboratory of Cell and Developmental Signaling, National Cancer Institute-Frederick, National Institutes of Health, Frederick, Maryland 21702.
Lim J; From the Laboratory of Cell and Developmental Signaling, National Cancer Institute-Frederick, National Institutes of Health, Frederick, Maryland 21702.
Morrison DK; From the Laboratory of Cell and Developmental Signaling, National Cancer Institute-Frederick, National Institutes of Health, Frederick, Maryland 21702.
Daar IO; From the Laboratory of Cell and Developmental Signaling, National Cancer Institute-Frederick, National Institutes of Health, Frederick, Maryland 21702 daar@ncifcrf.gov.

J Biol Chem ; 289(26): 18556-68, 2014 Jun 27.

Article in En | MEDLINE | ID: mdl-24825906

Subject(s)

Cell Movement; Ephrin-B1/metabolism; Intracellular Signaling Peptides and Proteins/metabolism; JNK Mitogen-Activated Protein Kinases/metabolism; Cell Line; Cell Line, Tumor; Enzyme Activation; Ephrin-B1/genetics; Humans; Intracellular Signaling Peptides and Proteins/genetics; JNK Mitogen-Activated Protein Kinases/genetics; Phosphorylation; Protein Binding; rhoA GTP-Binding Protein/genetics; rhoA GTP-Binding Protein/metabolism

Key words

CNK1; Cell Migration; Eph; Ephrin; Ras Homolog Gene Family, Member A (RhoA); Scaffold Protein; Signal Transduction; c-Jun N-terminal Kinase (JNK)

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Full text: 1 Database: MEDLINE Main subject: Cell Movement / Ephrin-B1 / JNK Mitogen-Activated Protein Kinases / Intracellular Signaling Peptides and Proteins Limits: Humans Language: En Year: 2014 Type: Article

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