Unusual characteristics of the DNA binding domain of epigenetic regulatory protein MeCP2 determine its binding specificity.

Khrapunov, Sergei; Warren, Christopher; Cheng, Huiyong; Berko, Esther R; Greally, John M; Brenowitz, Michael

Khrapunov, Sergei; Warren, Christopher; Cheng, Huiyong; Berko, Esther R; Greally, John M; Brenowitz, Michael.

Affiliation

Khrapunov S; Department of Biochemistry and Department of Genetics, Albert Einstein College of Medicine of Yeshiva University , 1300 Morris Park Avenue, Bronx, New York 10461, United States.

Biochemistry ; 53(21): 3379-91, 2014 Jun 03.

Article in En | MEDLINE | ID: mdl-24828757

Subject(s)

DNA/chemistry; Epigenesis, Genetic; Methyl-CpG-Binding Protein 2/chemistry; Cations, Monovalent; CpG Islands; DNA, Single-Stranded/chemistry; Dimerization; Oligonucleotides/chemistry; Protein Binding; Protein Structure, Tertiary; Salts; Solutions; Static Electricity; Thermodynamics

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Full text: 1 Database: MEDLINE Main subject: DNA / Epigenesis, Genetic / Methyl-CpG-Binding Protein 2 Language: En Year: 2014 Type: Article

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Full text: 1 Database: MEDLINE Main subject: DNA / Epigenesis, Genetic / Methyl-CpG-Binding Protein 2 Language: En Year: 2014 Type: Article