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Discovery of MK-5046, a Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity.
Sebhat, Iyassu K; Franklin, Christopher; Lo, Michael M-C; Chen, David; Jewell, James P; Miller, Randy; Pang, Jianmei; Palyha, Oksana; Kan, Yanqing; Kelly, Theresa M; Guan, Xiao-Ming; Marsh, Donald J; Kosinski, Jennifer A; Metzger, Joseph M; Lyons, Kathryn; Dragovic, Jasminka; Guzzo, Peter R; Henderson, Alan J; Reitman, Marc L; Nargund, Ravi P; Wyvratt, Matthew J; Lin, Linus S.
Affiliation
  • Sebhat IK; Departments of Medicinal Chemistry.
  • Franklin C; Departments of Medicinal Chemistry.
  • Lo MM; Departments of Medicinal Chemistry.
  • Chen D; Departments of Medicinal Chemistry.
  • Jewell JP; Departments of Medicinal Chemistry.
  • Miller R; Drug Metabolism.
  • Pang J; Drug Metabolism.
  • Palyha O; Metabolic Diseases (Obesity).
  • Kan Y; Metabolic Diseases (Obesity).
  • Kelly TM; Metabolic Diseases (Obesity).
  • Guan XM; Metabolic Diseases (Obesity).
  • Marsh DJ; Metabolic Diseases (Obesity).
  • Kosinski JA; Metabolic Diseases (Obesity).
  • Metzger JM; Pharmacology.
  • Lyons K; Drug Metabolism.
  • Dragovic J; Drug Metabolism.
  • Guzzo PR; AMRI, 26 Corporate Circle, Albany, New York 12212, United States.
  • Henderson AJ; AMRI, 26 Corporate Circle, Albany, New York 12212, United States.
  • Reitman ML; Metabolic Diseases (Obesity).
  • Nargund RP; Departments of Medicinal Chemistry.
  • Wyvratt MJ; Departments of Medicinal Chemistry.
  • Lin LS; Departments of Medicinal Chemistry.
ACS Med Chem Lett ; 2(1): 43-7, 2011 Jan 13.
Article in En | MEDLINE | ID: mdl-24900253
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Full text: 1 Database: MEDLINE Language: En Year: 2011 Type: Article
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Full text: 1 Database: MEDLINE Language: En Year: 2011 Type: Article