Simultaneous determination of gabapentin, pregabalin, vigabatrin, and topiramate in plasma by HPLC with fluorescence detection.

Martinc, Bostjan; Roskar, Robert; Grabnar, Iztok; Vovk, Tomaz

Martinc, Bostjan; Roskar, Robert; Grabnar, Iztok; Vovk, Tomaz.

Affiliation

Martinc B; Faculty of Pharmacy, University of Ljubljana, Askerceva cesta 7, 1000 Ljubljana, Slovenia.
Roskar R; Faculty of Pharmacy, University of Ljubljana, Askerceva cesta 7, 1000 Ljubljana, Slovenia.
Grabnar I; Faculty of Pharmacy, University of Ljubljana, Askerceva cesta 7, 1000 Ljubljana, Slovenia.
Vovk T; Faculty of Pharmacy, University of Ljubljana, Askerceva cesta 7, 1000 Ljubljana, Slovenia. Electronic address: tomaz.vovk@ffa.uni-lj.si.

J Chromatogr B Analyt Technol Biomed Life Sci ; 962: 82-88, 2014 Jul 01.

Article in En | MEDLINE | ID: mdl-24907547

Subject(s)

Amines/blood; Anticonvulsants/blood; Cyclohexanecarboxylic Acids/blood; Fructose/analogs & derivatives; Vigabatrin/blood; gamma-Aminobutyric Acid/analogs & derivatives; Chromatography, High Pressure Liquid/methods; Drug Monitoring/methods; Fluorescence; Fructose/blood; Gabapentin; Humans; Limit of Detection; Pregabalin; Solid Phase Extraction/methods; Topiramate; gamma-Aminobutyric Acid/blood

Key words

Fluorescence detection; Gabapentin; Pregabalin; Therapeutic drug monitoring; Topiramate; Vigabatrin

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Full text: 1 Database: MEDLINE Main subject: Vigabatrin / Cyclohexanecarboxylic Acids / Fructose / Gamma-Aminobutyric Acid / Amines / Anticonvulsants Type of study: Diagnostic_studies Limits: Humans Language: En Year: 2014 Type: Article

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