Fatty acid-binding protein 4, a point of convergence for angiogenic and metabolic signaling pathways in endothelial cells.

Harjes, Ulrike; Bridges, Esther; McIntyre, Alan; Fielding, Barbara A; Harris, Adrian L

Harjes, Ulrike; Bridges, Esther; McIntyre, Alan; Fielding, Barbara A; Harris, Adrian L.

Affiliation

Harjes U; Weatherall Institute of Molecular Medicine, Department of Oncology, University of Oxford, OX3 9DS Oxford.
Bridges E; Weatherall Institute of Molecular Medicine, Department of Oncology, University of Oxford, OX3 9DS Oxford.
McIntyre A; Weatherall Institute of Molecular Medicine, Department of Oncology, University of Oxford, OX3 9DS Oxford.
Fielding BA; Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford OX3 7LJ, and; Department of Nutritional Sciences, University of Surrey, GU2 7WG Surrey, United Kingdom.
Harris AL; Weatherall Institute of Molecular Medicine, Department of Oncology, University of Oxford, OX3 9DS Oxford,. Electronic address: aharris.lab@imm.ox.ac.uk.

J Biol Chem ; 289(33): 23168-23176, 2014 Aug 15.

Article in En | MEDLINE | ID: mdl-24939870

Subject(s)

Fatty Acid-Binding Proteins/biosynthesis; Gene Expression Regulation/physiology; Human Umbilical Vein Endothelial Cells/metabolism; Neovascularization, Physiologic/physiology; Signal Transduction/physiology; Vascular Endothelial Growth Factor A/metabolism; Adaptor Proteins, Signal Transducing; Calcium-Binding Proteins; Fatty Acid-Binding Proteins/genetics; Forkhead Box Protein O1; Forkhead Transcription Factors/genetics; Forkhead Transcription Factors/metabolism; Human Umbilical Vein Endothelial Cells/cytology; Humans; Intercellular Signaling Peptides and Proteins/genetics; Intercellular Signaling Peptides and Proteins/metabolism; Neoplasm Proteins/genetics; Neoplasm Proteins/metabolism; Neoplasms/blood supply; Neoplasms/genetics; Neoplasms/metabolism; Neoplasms/pathology; Neovascularization, Pathologic/genetics; Neovascularization, Pathologic/metabolism; Neovascularization, Pathologic/pathology; Promoter Regions, Genetic/physiology; Receptors, Notch/genetics; Receptors, Notch/metabolism; Vascular Endothelial Growth Factor A/genetics

Key words

Angiogenesis; DLL4; Endothelial Cell; FOXO; Fatty Acid-binding Protein; Metabolism; Notch Pathway; Vascular Endothelial Growth Factor (VEGF)

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Full text: 1 Database: MEDLINE Main subject: Signal Transduction / Gene Expression Regulation / Neovascularization, Physiologic / Vascular Endothelial Growth Factor A / Fatty Acid-Binding Proteins / Human Umbilical Vein Endothelial Cells Limits: Humans Language: En Year: 2014 Type: Article

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