Subcutaneous tocilizumab versus placebo in combination with disease-modifying antirheumatic drugs in patients with rheumatoid arthritis.

Kivitz, Alan; Olech, Ewa; Borofsky, Michael; Zazueta, Beatriz M; Navarro-Sarabia, Federico; Radominski, Sebastião C; Merrill, Joan T; Rowell, Lucy; Nasmyth-Miller, Clare; Bao, Min; Wright, Stephen; Pope, Janet E

Kivitz, Alan; Olech, Ewa; Borofsky, Michael; Zazueta, Beatriz M; Navarro-Sarabia, Federico; Radominski, Sebastião C; Merrill, Joan T; Rowell, Lucy; Nasmyth-Miller, Clare; Bao, Min; Wright, Stephen; Pope, Janet E.

Affiliation

Kivitz A; Altoona Center for Clinical Research, Duncansville, Pennsylvania.

Arthritis Care Res (Hoboken) ; 66(11): 1653-61, 2014 Nov.

Article in En | MEDLINE | ID: mdl-24942540

Subject(s)

Antibodies, Monoclonal, Humanized/therapeutic use; Antibodies, Monoclonal/therapeutic use; Antirheumatic Agents/therapeutic use; Arthritis, Rheumatoid/drug therapy; Receptors, Interleukin-6/antagonists & inhibitors; Adult; Antibodies, Monoclonal/administration & dosage; Antibodies, Monoclonal/adverse effects; Antibodies, Monoclonal, Humanized/administration & dosage; Antibodies, Monoclonal, Humanized/adverse effects; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Subcutaneous; Male; Middle Aged; Receptors, Interleukin-6/immunology; Treatment Outcome

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Full text: 1 Database: MEDLINE Main subject: Arthritis, Rheumatoid / Antirheumatic Agents / Receptors, Interleukin-6 / Antibodies, Monoclonal, Humanized / Antibodies, Monoclonal Type of study: Clinical_trials Limits: Adult / Female / Humans / Male / Middle aged Language: En Year: 2014 Type: Article

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