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Hearts from mice fed a non-obesogenic high-fat diet exhibit changes in their oxidative state, calcium and mitochondria in parallel with increased susceptibility to reperfusion injury.
Littlejohns, Ben; Pasdois, Philippe; Duggan, Simon; Bond, Andrew R; Heesom, Kate; Jackson, Christopher L; Angelini, Gianni D; Halestrap, Andrew P; Suleiman, M-Saadeh.
Affiliation
  • Littlejohns B; Bristol Heart Institute, School of Clinical Sciences, Faculty of Medicine and Dentistry, University of Bristol, Bristol, United Kingdom.
  • Pasdois P; Bioénergétique et Métabolisme, Institut de Rythmologie et Modélisation Cardiaque, Université de Bordeaux, Pessac, France.
  • Duggan S; Oxford Heart Centre, John Radcliffe Hospital, Oxford, United Kingdom.
  • Bond AR; Bristol Heart Institute, School of Clinical Sciences, Faculty of Medicine and Dentistry, University of Bristol, Bristol, United Kingdom.
  • Heesom K; Proteomics Facility, Faculty of Medical and Veterinary Sciences, University of Bristol, Bristol, United Kingdom.
  • Jackson CL; Bristol Heart Institute, School of Clinical Sciences, Faculty of Medicine and Dentistry, University of Bristol, Bristol, United Kingdom.
  • Angelini GD; Bristol Heart Institute, School of Clinical Sciences, Faculty of Medicine and Dentistry, University of Bristol, Bristol, United Kingdom.
  • Halestrap AP; School of Biochemistry, Faculty of Medical and Veterinary Sciences, University of Bristol, Bristol, United Kingdom.
  • Suleiman MS; Bristol Heart Institute, School of Clinical Sciences, Faculty of Medicine and Dentistry, University of Bristol, Bristol, United Kingdom.
PLoS One ; 9(6): e100579, 2014.
Article in En | MEDLINE | ID: mdl-24950187
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Full text: 1 Database: MEDLINE Main subject: Myocardial Reperfusion Injury / Calcium / Diet, High-Fat / Mitochondria / Myocardium Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Year: 2014 Type: Article
Fulltext
Print
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Myocardial Reperfusion Injury / Calcium / Diet, High-Fat / Mitochondria / Myocardium Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Year: 2014 Type: Article