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Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation.
Souchek, J J; Baine, M J; Lin, C; Rachagani, S; Gupta, S; Kaur, S; Lester, K; Zheng, D; Chen, S; Smith, L; Lazenby, A; Johansson, S L; Jain, M; Batra, S K.
Affiliation
  • Souchek JJ; Fred & Pamela Buffet Cancer Center, Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, USA.
  • Baine MJ; Fred & Pamela Buffet Cancer Center, Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, USA.
  • Lin C; Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE, USA.
  • Rachagani S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
  • Gupta S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
  • Kaur S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
  • Lester K; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
  • Zheng D; Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE, USA.
  • Chen S; Department of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Smith L; Department of Biostatistics, University of Nebraska Medical Center, Omaha, NE, USA.
  • Lazenby A; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
  • Johansson SL; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
  • Jain M; 1] Fred & Pamela Buffet Cancer Center, Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, USA [2] Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
  • Batra SK; 1] Fred & Pamela Buffet Cancer Center, Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE, USA [2] Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
Br J Cancer ; 111(6): 1139-49, 2014 Sep 09.
Article in En | MEDLINE | ID: mdl-25025965
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Full text: 1 Database: MEDLINE Main subject: Pancreatic Neoplasms / Radiation-Sensitizing Agents / Radiation Tolerance / Adenocarcinoma / Cholesterol / Diphosphonates / Geranyltranstransferase / Imidazoles Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2014 Type: Article
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Pancreatic Neoplasms / Radiation-Sensitizing Agents / Radiation Tolerance / Adenocarcinoma / Cholesterol / Diphosphonates / Geranyltranstransferase / Imidazoles Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2014 Type: Article