Orthogonal functionalisation of &#945;-helix mimetics.

Barnard, Anna; Long, Kérya; Yeo, David J; Miles, Jennifer A; Azzarito, Valeria; Burslem, George M; Prabhakaran, Panchami; A Edwards, Thomas; Wilson, Andrew J

Orthogonal functionalisation of α-helix mimetics.

Barnard, Anna; Long, Kérya; Yeo, David J; Miles, Jennifer A; Azzarito, Valeria; Burslem, George M; Prabhakaran, Panchami; A Edwards, Thomas; Wilson, Andrew J.

Affiliation

Barnard A; School of Chemistry, University of Leeds, Woodhouse Lane, Leeds, LS2 9JT, UK.

Org Biomol Chem ; 12(35): 6794-9, 2014 Sep 21.

Article in En | MEDLINE | ID: mdl-25065821

Subject(s)

Proto-Oncogene Proteins c-mdm2/chemistry; Tumor Suppressor Protein p53/chemistry; Amides/chemistry; Biomimetics; Click Chemistry; Humans; Inhibitory Concentration 50; Myeloid Cell Leukemia Sequence 1 Protein/chemistry; Protein Binding; Protein Interaction Mapping; Protein Structure, Secondary; Proteomics/methods; Proto-Oncogene Proteins c-mdm2/antagonists & inhibitors; Solvents/chemistry; Surface Properties; Tumor Suppressor Protein p53/antagonists & inhibitors; bcl-X Protein/chemistry

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Full text: 1 Database: MEDLINE Main subject: Tumor Suppressor Protein p53 / Proto-Oncogene Proteins c-mdm2 Limits: Humans Language: En Year: 2014 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Tumor Suppressor Protein p53 / Proto-Oncogene Proteins c-mdm2 Limits: Humans Language: En Year: 2014 Type: Article