Polymorphisms of endotoxin pathway and endotoxin exposure: in vitro IgE synthesis and replication in a birth cohort.

Sahiner, U M; Semic-Jusufagic, A; Curtin, J A; Birben, E; Belgrave, D; Sackesen, C; Simpson, A; Yavuz, T S; Akdis, C A; Custovic, A; Kalayci, O

Sahiner, U M; Semic-Jusufagic, A; Curtin, J A; Birben, E; Belgrave, D; Sackesen, C; Simpson, A; Yavuz, T S; Akdis, C A; Custovic, A; Kalayci, O.

Affiliation

Sahiner UM; Pediatric Allergy and Asthma Unit, Hacettepe University School of Medicine, Ankara, Turkey.

Allergy ; 69(12): 1648-58, 2014 Dec.

Article in En | MEDLINE | ID: mdl-25102764

Subject(s)

Endotoxins/immunology; Immunoglobulin E/biosynthesis; Immunoglobulin E/immunology; Polymorphism, Genetic; Adolescent; Alleles; Asthma/diagnosis; Asthma/genetics; Asthma/immunology; Cells, Cultured; Child; Cohort Studies; Endotoxins/metabolism; Environmental Exposure; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Hypersensitivity, Immediate/diagnosis; Hypersensitivity, Immediate/genetics; Hypersensitivity, Immediate/immunology; In Vitro Techniques; Leukocytes, Mononuclear/immunology; Leukocytes, Mononuclear/metabolism; Polymorphism, Single Nucleotide; Signal Transduction

Key words

IgE; asthma; atopy; endotoxin; gene

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Full text: 1 Database: MEDLINE Main subject: Polymorphism, Genetic / Immunoglobulin E / Endotoxins Type of study: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Child / Humans Language: En Year: 2014 Type: Article

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