VEGF-C-dependent stimulation of lymphatic function ameliorates experimental inflammatory bowel disease.

D'Alessio, Silvia; Correale, Carmen; Tacconi, Carlotta; Gandelli, Alessandro; Pietrogrande, Giovanni; Vetrano, Stefania; Genua, Marco; Arena, Vincenzo; Spinelli, Antonino; Peyrin-Biroulet, Laurent; Fiocchi, Claudio; Danese, Silvio

D'Alessio, Silvia; Correale, Carmen; Tacconi, Carlotta; Gandelli, Alessandro; Pietrogrande, Giovanni; Vetrano, Stefania; Genua, Marco; Arena, Vincenzo; Spinelli, Antonino; Peyrin-Biroulet, Laurent; Fiocchi, Claudio; Danese, Silvio.

J Clin Invest ; 124(9): 3863-78, 2014 Sep.

Article in En | MEDLINE | ID: mdl-25105363

Subject(s)

Inflammatory Bowel Diseases/etiology; Lymphangiogenesis/physiology; Vascular Endothelial Growth Factor C/physiology; Animals; Colon/immunology; Disease Models, Animal; Female; Humans; Inflammatory Bowel Diseases/drug therapy; Inflammatory Bowel Diseases/immunology; Lymphatic Vessels/physiology; Macrophage Activation; Macrophages/physiology; Male; Mice; Mice, Inbred C57BL; Signal Transduction; Vascular Endothelial Growth Factor Receptor-3/physiology

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Full text: 1 Database: MEDLINE Main subject: Inflammatory Bowel Diseases / Vascular Endothelial Growth Factor C / Lymphangiogenesis Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Year: 2014 Type: Article

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