Snail regulated by PKC/GSK-3ß pathway is crucial for EGF-induced epithelial-mesenchymal transition (EMT) of cancer cells.

Liu, Zong-cai; Chen, Xiao-hui; Song, Hai-xing; Wang, Hong-sheng; Zhang, Ge; Wang, Hao; Chen, Dan-yang; Fang, Rui; Liu, Hao; Cai, Shao-hui; Du, Jun

Liu, Zong-cai; Chen, Xiao-hui; Song, Hai-xing; Wang, Hong-sheng; Zhang, Ge; Wang, Hao; Chen, Dan-yang; Fang, Rui; Liu, Hao; Cai, Shao-hui; Du, Jun.

Affiliation

Liu ZC; Department of Microbial and Biochemical Pharmacy School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, Guangdong, 510006, People's Republic of China.

Cell Tissue Res ; 358(2): 491-502, 2014 Nov.

Article in En | MEDLINE | ID: mdl-25124796

Subject(s)

Epidermal Growth Factor/pharmacology; Epithelial-Mesenchymal Transition/drug effects; Glycogen Synthase Kinase 3/metabolism; Neoplasms/pathology; Protein Kinase C/metabolism; Signal Transduction/drug effects; Transcription Factors/metabolism; Cell Line, Tumor; Cell Movement/drug effects; Cell Nucleus/drug effects; Cell Nucleus/metabolism; Glycogen Synthase Kinase 3 beta; Humans; Neoplasm Invasiveness; Neoplasms/enzymology; Neoplasms/genetics; Protein Stability/drug effects; Protein Transport/drug effects; Snail Family Transcription Factors; Transcription Factors/genetics; Transcription, Genetic/drug effects; Up-Regulation/drug effects

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Full text: 1 Database: MEDLINE Main subject: Transcription Factors / Protein Kinase C / Signal Transduction / Glycogen Synthase Kinase 3 / Epidermal Growth Factor / Epithelial-Mesenchymal Transition / Neoplasms Limits: Humans Language: En Year: 2014 Type: Article

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