Androgen deprivation-induced NCoA2 promotes metastatic and castration-resistant prostate cancer.

Qin, Jun; Lee, Hui-Ju; Wu, San-Pin; Lin, Shih-Chieh; Lanz, Rainer B; Creighton, Chad J; DeMayo, Francesco J; Tsai, Sophia Y; Tsai, Ming-Jer

Qin, Jun; Lee, Hui-Ju; Wu, San-Pin; Lin, Shih-Chieh; Lanz, Rainer B; Creighton, Chad J; DeMayo, Francesco J; Tsai, Sophia Y; Tsai, Ming-Jer.

J Clin Invest ; 124(11): 5013-26, 2014 Nov.

Article in En | MEDLINE | ID: mdl-25295534

Subject(s)

Nuclear Receptor Coactivator 2/metabolism; Prostate/metabolism; Prostatic Intraepithelial Neoplasia/metabolism; Prostatic Neoplasms, Castration-Resistant/metabolism; Androgens/physiology; Animals; Cell Line, Tumor; Disease Progression; Humans; Kaplan-Meier Estimate; MAP Kinase Signaling System; Male; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Hormone-Dependent/metabolism; Neoplasms, Hormone-Dependent/mortality; Neoplasms, Hormone-Dependent/pathology; PTEN Phosphohydrolase/metabolism; Proportional Hazards Models; Prostatic Intraepithelial Neoplasia/mortality; Prostatic Intraepithelial Neoplasia/secondary; Prostatic Neoplasms, Castration-Resistant/mortality; Prostatic Neoplasms, Castration-Resistant/pathology; Up-Regulation

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Full text: 1 Database: MEDLINE Main subject: Prostate / Prostatic Intraepithelial Neoplasia / Nuclear Receptor Coactivator 2 / Prostatic Neoplasms, Castration-Resistant Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Year: 2014 Type: Article

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