Cobalt chloride attenuates oxidative stress and inflammation through NF-&#954;B inhibition in human renal proximal tubular epithelial cells.

Oh, Se Won; Lee, Yun-Mi; Kim, Sejoong; Chin, Ho Jun; Chae, Dong-Wan; Na, Ki Young

Cobalt chloride attenuates oxidative stress and inflammation through NF-κB inhibition in human renal proximal tubular epithelial cells.

Oh, Se Won; Lee, Yun-Mi; Kim, Sejoong; Chin, Ho Jun; Chae, Dong-Wan; Na, Ki Young.

Affiliation

Oh SW; Department of Internal Medicine, Inje University College of Medicine, Ilsan Paik Hospital, Goyang, Korea.
Lee YM; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Kim S; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. ; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Chin HJ; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. ; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Chae DW; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. ; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
Na KY; Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea. ; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.

J Korean Med Sci ; 29 Suppl 2: S139-45, 2014 Sep.

Article in En | MEDLINE | ID: mdl-25317018

Subject(s)

Cobalt/pharmacology; Inflammation; NF-kappa B/metabolism; Oxidative Stress/drug effects; Cell Line; Chemokine CCL2/metabolism; Chemokine CCL5/metabolism; Epithelial Cells/cytology; Epithelial Cells/metabolism; Heme Oxygenase-1/antagonists & inhibitors; Heme Oxygenase-1/genetics; Heme Oxygenase-1/metabolism; Humans; Interferon-gamma/pharmacology; Kidney Tubules, Proximal/cytology; NF-kappa B/antagonists & inhibitors; NF-kappa B/genetics; NF-kappa B p50 Subunit/genetics; NF-kappa B p50 Subunit/metabolism; Phosphorylation; Protein Binding; RNA Interference; RNA, Small Interfering/metabolism; Transcription Factor RelA/metabolism; Tumor Necrosis Factor-alpha/pharmacology

Key words

Cobalt Chloride; Hemeoxygenase-1; Inflammation; Nuclear Factor-kappa B; Renal Tubular Epithelial Cells

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: NF-kappa B / Cobalt / Oxidative Stress / Inflammation Limits: Humans Language: En Year: 2014 Type: Article

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: NF-kappa B / Cobalt / Oxidative Stress / Inflammation Limits: Humans Language: En Year: 2014 Type: Article