A synthesized nostocionone derivative potentiates programmed cell death in human T-cell leukemia Jurkat cells through mitochondria via the release of endonuclease G.

Itoh, Tomohiro; Muramatsu, Yuji; Masu, Masayo; Tsuge, Ayaka; Taniguchi, Masaki; Ninomiya, Masayuki; Ando, Masashi; Tsukamasa, Yasuyuki; Koketsu, Mamoru

Itoh, Tomohiro; Muramatsu, Yuji; Masu, Masayo; Tsuge, Ayaka; Taniguchi, Masaki; Ninomiya, Masayuki; Ando, Masashi; Tsukamasa, Yasuyuki; Koketsu, Mamoru.

Affiliation

Itoh T; a Laboratory of Aquatic Food Science, Department of Fisheries, Faculty of Agriculture , Kinki University , Nara , Japan.

Nutr Cancer ; 66(8): 1414-23, 2014.

Article in En | MEDLINE | ID: mdl-25333640

Subject(s)

Apoptosis/drug effects; DNA Fragmentation/drug effects; Endodeoxyribonucleases/metabolism; Leukemia/pathology; Mitochondria/drug effects; Nostoc commune/metabolism; Acetylcysteine/pharmacology; Humans; Jurkat Cells; Membrane Potential, Mitochondrial/drug effects; Reactive Oxygen Species/metabolism

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Full text: 1 Database: MEDLINE Main subject: Leukemia / Apoptosis / Endodeoxyribonucleases / Nostoc commune / DNA Fragmentation / Mitochondria Limits: Humans Language: En Year: 2014 Type: Article

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