Loss of keratinocyte focal adhesion kinase stimulates dermal proteolysis through upregulation of MMP9 in wound healing.

Wong, Victor W; Garg, Ravi K; Sorkin, Michael; Rustad, Kristine C; Akaishi, Satoshi; Levi, Kemal; Nelson, Emily R; Tran, Misha; Rennert, Robert; Liu, Wei; Longaker, Michael T; Dauskardt, Reinhold H; Gurtner, Geoffrey C

Wong, Victor W; Garg, Ravi K; Sorkin, Michael; Rustad, Kristine C; Akaishi, Satoshi; Levi, Kemal; Nelson, Emily R; Tran, Misha; Rennert, Robert; Liu, Wei; Longaker, Michael T; Dauskardt, Reinhold H; Gurtner, Geoffrey C.

Affiliation

Wong VW; *Department of Surgery, Stanford University School of Medicine, Stanford, CA; and Department of Materials Science and Engineering, Stanford University, Stanford, CA.

Ann Surg ; 260(6): 1138-46, 2014 Dec.

Article in En | MEDLINE | ID: mdl-25389925

Subject(s)

Focal Adhesion Protein-Tyrosine Kinases/genetics; Keratinocytes/ultrastructure; RNA/genetics; Skin/injuries; Up-Regulation; Wound Healing; Wounds and Injuries/genetics; Animals; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Focal Adhesion Protein-Tyrosine Kinases/biosynthesis; Humans; Immunoblotting; Immunohistochemistry; In Situ Hybridization; Infant, Newborn; Keratinocytes/metabolism; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Proteolysis; Wounds and Injuries/metabolism; Wounds and Injuries/pathology

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Full text: 1 Database: MEDLINE Main subject: Skin / Wound Healing / Wounds and Injuries / RNA / Keratinocytes / Up-Regulation / Focal Adhesion Protein-Tyrosine Kinases Type of study: Prognostic_studies Limits: Animals / Humans / Newborn Language: En Year: 2014 Type: Article

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