Non-digestible oligosaccharides modulate intestinal immune activation and suppress cow's milk allergic symptoms.

Kerperien, J; Jeurink, P V; Wehkamp, T; van der Veer, A; van de Kant, H J G; Hofman, G A; van Esch, E C A M; Garssen, J; Willemsen, L E M; Knippels, L M J

Kerperien, J; Jeurink, P V; Wehkamp, T; van der Veer, A; van de Kant, H J G; Hofman, G A; van Esch, E C A M; Garssen, J; Willemsen, L E M; Knippels, L M J.

Affiliation

Kerperien J; Division of Pharmacology, Department of Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, The Netherlands.

Pediatr Allergy Immunol ; 25(8): 747-54, 2014 Dec.

Article in En | MEDLINE | ID: mdl-25410019

Subject(s)

Allergens/metabolism; Complex Mixtures/metabolism; Milk Hypersensitivity/immunology; Oligosaccharides/metabolism; T-Lymphocyte Subsets/immunology; Allergens/immunology; Animals; Cattle; Complex Mixtures/immunology; Dietary Supplements; Digestion; Forkhead Transcription Factors/metabolism; Humans; Immunity, Innate; Immunization; Immunomodulation; Interleukin-10/metabolism; Intestinal Mucosa/immunology; Mice; Mice, Inbred C3H; Milk/immunology; Oligosaccharides/immunology; Transforming Growth Factor beta/metabolism

Key words

cow's milk allergy; intestinal mucosa; non-digestible oligosaccharides; prevention; regulatory T cells

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Full text: 1 Database: MEDLINE Main subject: Oligosaccharides / Allergens / T-Lymphocyte Subsets / Milk Hypersensitivity / Complex Mixtures Type of study: Diagnostic_studies / Guideline Limits: Animals / Humans Language: En Year: 2014 Type: Article

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