Tyrosine-kinase defect of the insulin receptor in cultured fibroblasts from patients with lipoatropic diabetes.

Magré, J; Grigorescu, F; Reynet, C; Caron, M; Capony, J P; White, M F; Picard, J; Mirouze, J; Capeau, J

Magré, J; Grigorescu, F; Reynet, C; Caron, M; Capony, J P; White, M F; Picard, J; Mirouze, J; Capeau, J.

Affiliation

Magré J; Laboratory of Cell Biology INSERM U181, Saint Antoine Faculty of Medicine, Paris, France.

J Clin Endocrinol Metab ; 69(1): 142-50, 1989 Jul.

Article in En | MEDLINE | ID: mdl-2543688

Subject(s)

Diabetes Mellitus, Lipoatrophic/metabolism; Insulin Resistance; Protein-Tyrosine Kinases/analysis; Receptor, Insulin/analysis; Adolescent; Adult; Autoradiography; Binding Sites; Binding, Competitive; Cells, Cultured; Child; Child, Preschool; Chromatography, Affinity; Female; Humans; Infant; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases/metabolism; Receptor, Insulin/metabolism; Receptors, Cell Surface/analysis; Receptors, Somatomedin; Serine/metabolism; Tyrosine/immunology; Tyrosine/metabolism

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Database: MEDLINE Main subject: Protein-Tyrosine Kinases / Insulin Resistance / Receptor, Insulin / Diabetes Mellitus, Lipoatrophic Type of study: Prognostic_studies / Qualitative_research Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Infant Language: En Year: 1989 Type: Article

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