Effects of methylphenidate on the behavior of male 5xFAD mice.

Schneider, F; Baldauf, K; Wetzel, W; Reymann, K G

Schneider, F; Baldauf, K; Wetzel, W; Reymann, K G.

Affiliation

Schneider F; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg D-39120, Germany. Electronic address: Franziska.Schneider@dzne.de.
Baldauf K; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg D-39120, Germany. Electronic address: Kathrin.Baldauf@dzne.de.
Wetzel W; Leibniz Institute for Neurobiology, Brenneckestr. 6, Magdeburg D-39118, Germany. Electronic address: Wolfram.Wetzel@lin-magdeburg.de.
Reymann KG; German Centre for Neurodegenerative Diseases (DZNE), Magdeburg D-39120, Germany; Leibniz Institute for Neurobiology, Brenneckestr. 6, Magdeburg D-39118, Germany. Electronic address: Klaus.Reymann@dzne.de.

Pharmacol Biochem Behav ; 128: 68-77, 2015 Jan.

Article in En | MEDLINE | ID: mdl-25449360

Subject(s)

Behavior, Animal/drug effects; Central Nervous System Stimulants/pharmacology; Methylphenidate/pharmacology; Alzheimer Disease/drug therapy; Alzheimer Disease/genetics; Alzheimer Disease/psychology; Amyloid beta-Protein Precursor/genetics; Animals; Anxiety/drug therapy; Behavior, Animal/physiology; Disease Models, Animal; Exploratory Behavior/drug effects; Habituation, Psychophysiologic/drug effects; Humans; Male; Maze Learning/drug effects; Mice; Mice, Transgenic; Motor Activity/drug effects; Mutant Proteins/genetics; Presenilin-1/genetics

Key words

5xFAD mice; Apathy; Cognitive deficits; Methylphenidate; Pharmacological stimulation

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Full text: 1 Database: MEDLINE Main subject: Behavior, Animal / Central Nervous System Stimulants / Methylphenidate Type of study: Prognostic_studies Limits: Animals / Humans / Male Language: En Year: 2015 Type: Article

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