Positional changes of a pluripotency marker gene during structural reorganization of fibroblast nuclei in cloned early bovine embryos.

Popken, Jens; Koehler, Daniela; Brero, Alessandro; Wuensch, Annegret; Guengoer, Tuna; Thormeyer, Tobias; Wolf, Eckhard; Cremer, Thomas; Zakhartchenko, Valeri

Popken, Jens; Koehler, Daniela; Brero, Alessandro; Wuensch, Annegret; Guengoer, Tuna; Thormeyer, Tobias; Wolf, Eckhard; Cremer, Thomas; Zakhartchenko, Valeri.

Affiliation

Popken J; a Division of Anthropology and Human Genetics Biocenter ; LMU Munich ; Martinsried , Germany.

Nucleus ; 5(6): 542-54, 2014.

Article in En | MEDLINE | ID: mdl-25495180

Subject(s)

Cell Nucleus/genetics; Chromosomes/genetics; Embryonic Development; Nuclear Transfer Techniques; Transcriptional Activation; Animals; Blastocyst; Cattle; Cell Nucleus/metabolism; Cellular Reprogramming/genetics; Cloning, Organism; Embryo, Mammalian; Fibroblasts/cytology; Fibroblasts/metabolism; Gene Expression Regulation, Developmental; Octamer Transcription Factor-3/metabolism

Key words

(bovine) preimplantation embryos, chromosome territories, nuclear architecture, nuclear reprogramming, pluripotency gene activation, somatic cell nuclear transfer; BFF, bovine fetal fibroblasts; BTA, Bos taurus; CLSM, confocal laser scanning microscopy; CT, chromosome territory; eADS, enhanced absolute 3D distances to surfaces; IVF, in vitro fertilization; MGA, major embryonic genome activation; GOF, Oct4/Pou5f1-EGF

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Full text: 1 Database: MEDLINE Main subject: Transcriptional Activation / Cell Nucleus / Chromosomes / Embryonic Development / Nuclear Transfer Techniques Limits: Animals Language: En Year: 2014 Type: Article

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