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Total proteome analysis identifies migration defects as a major pathogenetic factor in immunoglobulin heavy chain variable region (IGHV)-unmutated chronic lymphocytic leukemia.
Eagle, Gina L; Zhuang, Jianguo; Jenkins, Rosalind E; Till, Kathleen J; Jithesh, Puthen V; Lin, Ke; Johnson, Gillian G; Oates, Melanie; Park, Kevin; Kitteringham, Neil R; Pettitt, Andrew R.
Affiliation
  • Eagle GL; From the ‡Department of Molecular and Clinical Cancer Medicine.
  • Zhuang J; From the ‡Department of Molecular and Clinical Cancer Medicine, j.zhuang@liverpool.ac.uk.
  • Jenkins RE; §MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool L69 3GA, UK;
  • Till KJ; From the ‡Department of Molecular and Clinical Cancer Medicine.
  • Jithesh PV; From the ‡Department of Molecular and Clinical Cancer Medicine.
  • Lin K; ¶Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool L7 8XP, UK.
  • Johnson GG; ¶Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool L7 8XP, UK.
  • Oates M; From the ‡Department of Molecular and Clinical Cancer Medicine.
  • Park K; §MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool L69 3GA, UK;
  • Kitteringham NR; §MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool L69 3GA, UK;
  • Pettitt AR; From the ‡Department of Molecular and Clinical Cancer Medicine, ¶Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool L7 8XP, UK a.r.pettitt@liverpool.ac.uk.
Mol Cell Proteomics ; 14(4): 933-45, 2015 Apr.
Article in En | MEDLINE | ID: mdl-25645933
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Full text: 1 Database: MEDLINE Main subject: Immunoglobulin Variable Region / Leukemia, Lymphocytic, Chronic, B-Cell / Cell Movement / Immunoglobulin Heavy Chains / Proteome / Proteomics / Mutation Type of study: Prognostic_studies Limits: Aged / Female / Humans / Male Language: En Year: 2015 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Immunoglobulin Variable Region / Leukemia, Lymphocytic, Chronic, B-Cell / Cell Movement / Immunoglobulin Heavy Chains / Proteome / Proteomics / Mutation Type of study: Prognostic_studies Limits: Aged / Female / Humans / Male Language: En Year: 2015 Type: Article