Positive and negative regulation of GlnR in validamycin A biosynthesis by binding to different loci in promoter region.

Qu, Shuang; Kang, Qianjin; Wu, Hang; Wang, Lei; Bai, Linquan

Qu, Shuang; Kang, Qianjin; Wu, Hang; Wang, Lei; Bai, Linquan.

Affiliation

Qu S; State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.

Appl Microbiol Biotechnol ; 99(11): 4771-83, 2015 Jun.

Article in En | MEDLINE | ID: mdl-25672849

Subject(s)

Gene Expression Regulation, Bacterial; Inositol/analogs & derivatives; Promoter Regions, Genetic; Repressor Proteins/metabolism; Streptomyces/genetics; Streptomyces/metabolism; Trans-Activators/metabolism; Binding Sites; DNA Footprinting; DNA Mutational Analysis; DNA, Bacterial/metabolism; Electrophoretic Mobility Shift Assay; Gene Knockout Techniques; Inositol/biosynthesis; Mutagenesis, Site-Directed; Protein Binding; Repressor Proteins/genetics; Trans-Activators/genetics

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Full text: 1 Database: MEDLINE Main subject: Repressor Proteins / Streptomyces / Gene Expression Regulation, Bacterial / Trans-Activators / Promoter Regions, Genetic / Inositol Type of study: Prognostic_studies Language: En Year: 2015 Type: Article

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