Synthesis and properties of 2'-deoxy-2',4'-difluoroarabinose-modified nucleic acids.

Martínez-Montero, Saúl; Deleavey, Glen F; Dierker-Viik, Arden; Lindovska, Petra; Ilina, Tatiana; Portella, Guillem; Orozco, Modesto; Parniak, Michael A; González, Carlos; Damha, Masad J

Martínez-Montero, Saúl; Deleavey, Glen F; Dierker-Viik, Arden; Lindovska, Petra; Ilina, Tatiana; Portella, Guillem; Orozco, Modesto; Parniak, Michael A; González, Carlos; Damha, Masad J.

Affiliation

Martínez-Montero S; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, QC H3A 0B8, Canada.
Deleavey GF; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, QC H3A 0B8, Canada.
Dierker-Viik A; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, QC H3A 0B8, Canada.
Lindovska P; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, QC H3A 0B8, Canada.
Ilina T; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, 450 Technology Drive, Pittsburgh, Pennsylvania 15219-3143, United States.
Portella G; §Joint IRB-BSC program on Computational Biology, Institute for Research in Biomedicine, Barcelona Supercomputing Center, and Department of Biochemistry, University of Barcelona, Baldiri Reixac 10-12, 08028 Barcelona, Spain.
Orozco M; §Joint IRB-BSC program on Computational Biology, Institute for Research in Biomedicine, Barcelona Supercomputing Center, and Department of Biochemistry, University of Barcelona, Baldiri Reixac 10-12, 08028 Barcelona, Spain.
Parniak MA; Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, 450 Technology Drive, Pittsburgh, Pennsylvania 15219-3143, United States.
González C; â¥Instituto de Química Física Rocasolano, CSIC, C/ Serrano 119, 28006 Madrid, Spain.
Damha MJ; Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, QC H3A 0B8, Canada.

J Org Chem ; 80(6): 3083-91, 2015 Mar 20.

Article in En | MEDLINE | ID: mdl-25723361

Subject(s)

Arabinose/analogs & derivatives; DNA/chemistry; DNA/chemical synthesis; RNA/chemistry; RNA/chemical synthesis; Arabinose/chemistry; Molecular Structure

Fulltext

XML

PubMed Links

Search on Google