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Dopaminergic denervation severity depends on COMT Val158Met polymorphism in Parkinson's disease.
Muellner, Julia; Gharrad, Iman; Habert, Marie-Odile; Kas, Aurélie; Martini, Jean-Baptiste; Cormier-Dequaire, Florence; Tahiri, Khadija; Vidailhet, Marie; Meier, Niklaus; Brice, Alexis; Schuepbach, Michael; Mallet, Alain; Hartmann, Andreas; Corvol, Jean-Christophe.
Affiliation
  • Muellner J; Department of Neurology, Inselspital, Freiburgstrasse 100, 3010 Bern, Switzerland; Sorbonne University, UPMC Paris 06 UMR S 1127, and Inserm U 1127 and CIC 1422, and CNRS UR 7225, and ICM, 75013 Paris, France.
  • Gharrad I; Sorbonne University, UPMC Paris 06 UMR S 1127, and Inserm U 1127 and CIC 1422, and CNRS UR 7225, and ICM, 75013 Paris, France.
  • Habert MO; AP-HP, Department of Nuclear Medicine, Pitié-Salpêtrière Hospital, Sorbonne University, UPMC Paris 06, CNRS UMR 7371, INSERM U1146, 75013 Paris, France.
  • Kas A; AP-HP, Department of Nuclear Medicine, Pitié-Salpêtrière Hospital, Sorbonne University, UPMC Paris 06, CNRS UMR 7371, INSERM U1146, 75013 Paris, France.
  • Martini JB; AP-HP, Department of Nuclear Medicine, Pitié-Salpêtrière Hospital, Sorbonne University, UPMC Paris 06, CNRS UMR 7371, INSERM U1146, 75013 Paris, France; Centre d'Analyse et de Traitement des Images (CATI), 75013 Paris, France.
  • Cormier-Dequaire F; Sorbonne University, UPMC Paris 06 UMR S 1127, and Inserm U 1127 and CIC 1422, and CNRS UR 7225, and ICM, 75013 Paris, France; AP-HP, Department of Neurology, Pitié-Salpêtrière Hospital, 75013 Paris, France.
  • Tahiri K; Sorbonne University, UPMC Paris 06 UMR S 1127, and Inserm U 1127 and CIC 1422, and CNRS UR 7225, and ICM, 75013 Paris, France.
  • Vidailhet M; Sorbonne University, UPMC Paris 06 UMR S 1127, and Inserm U 1127 and CIC 1422, and CNRS UR 7225, and ICM, 75013 Paris, France; AP-HP, Department of Neurology, Pitié-Salpêtrière Hospital, 75013 Paris, France.
  • Meier N; Department of Neurology, Inselspital, Freiburgstrasse 100, 3010 Bern, Switzerland; Sorbonne University, UPMC Paris 06 UMR S 1127, and Inserm U 1127 and CIC 1422, and CNRS UR 7225, and ICM, 75013 Paris, France.
  • Brice A; Sorbonne University, UPMC Paris 06 UMR S 1127, and Inserm U 1127 and CIC 1422, and CNRS UR 7225, and ICM, 75013 Paris, France.
  • Schuepbach M; Department of Neurology, Inselspital, Freiburgstrasse 100, 3010 Bern, Switzerland; Sorbonne University, UPMC Paris 06 UMR S 1127, and Inserm U 1127 and CIC 1422, and CNRS UR 7225, and ICM, 75013 Paris, France.
  • Mallet A; Inserm U436, Laboratory of Mathematical and Statistical Modelisation in Biology and Medicine, Pitié-Salpêtrière Hospital, 91 bd de l'hôpital, 75634 Paris Cedex 13, France; APHP, Clinical Research Unit, Department of Biostatistics, Pitié-Salpêtrière Hospital, 75013 Paris, France.
  • Hartmann A; Sorbonne University, UPMC Paris 06 UMR S 1127, and Inserm U 1127 and CIC 1422, and CNRS UR 7225, and ICM, 75013 Paris, France; AP-HP, Department of Neurology, Pitié-Salpêtrière Hospital, 75013 Paris, France.
  • Corvol JC; Sorbonne University, UPMC Paris 06 UMR S 1127, and Inserm U 1127 and CIC 1422, and CNRS UR 7225, and ICM, 75013 Paris, France; AP-HP, Department of Neurology, Pitié-Salpêtrière Hospital, 75013 Paris, France. Electronic address: jean-christophe.corvol@psl.aphp.fr.
Parkinsonism Relat Disord ; 21(5): 471-6, 2015 May.
Article in En | MEDLINE | ID: mdl-25753458
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Full text: 1 Database: MEDLINE Main subject: Parkinson Disease / Valine / Catechol O-Methyltransferase / Polymorphism, Single Nucleotide / Dopaminergic Neurons / Methionine Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Year: 2015 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Parkinson Disease / Valine / Catechol O-Methyltransferase / Polymorphism, Single Nucleotide / Dopaminergic Neurons / Methionine Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Year: 2015 Type: Article