A role for KMT1c in monocyte to dendritic cell differentiation: Epigenetic regulation of monocyte differentiation.

Wierda, Rutger J; Goedhart, Marieke; van Eggermond, Marja C J A; Muggen, Alice F; Miggelbrink, Xanne M; Geutskens, Sacha B; van Zwet, Erik; Haasnoot, Geert W; van den Elsen, Peter J

Wierda, Rutger J; Goedhart, Marieke; van Eggermond, Marja C J A; Muggen, Alice F; Miggelbrink, Xanne M; Geutskens, Sacha B; van Zwet, Erik; Haasnoot, Geert W; van den Elsen, Peter J.

Affiliation

Wierda RJ; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.
Goedhart M; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.
van Eggermond MC; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.
Muggen AF; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.
Miggelbrink XM; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.
Geutskens SB; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.
van Zwet E; Department of Medical Statistics, Leiden University Medical Center, Leiden, The Netherlands.
Haasnoot GW; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.
van den Elsen PJ; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands; Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands. Electronic address: pjvdelsen@lumc.nl.

Hum Immunol ; 76(6): 431-7, 2015 Jun.

Article in En | MEDLINE | ID: mdl-25843229

Subject(s)

Dendritic Cells/metabolism; Epigenesis, Genetic; Histocompatibility Antigens/genetics; Histone-Lysine N-Methyltransferase/genetics; Monocytes/metabolism; Acetylation; Adenosine/analogs & derivatives; Adenosine/pharmacology; Azepines/pharmacology; Cell Adhesion Molecules/genetics; Cell Adhesion Molecules/metabolism; Cell Differentiation/drug effects; Chromatin/chemistry; Chromatin/drug effects; Chromatin/metabolism; Chromatin Assembly and Disassembly/drug effects; Dendritic Cells/cytology; Dendritic Cells/drug effects; Gene Expression Profiling; Histocompatibility Antigens/metabolism; Histone-Lysine N-Methyltransferase/metabolism; Humans; Lectins, C-Type/genetics; Lectins, C-Type/metabolism; Methylation; Monocytes/cytology; Monocytes/drug effects; Primary Cell Culture; Quinazolines/pharmacology; Receptors, Cell Surface/genetics; Receptors, Cell Surface/metabolism; Signal Transduction; Transcription, Genetic

Key words

Dendritic cells; Epigenetics; Macrophages; Monocyte differentiation; Monocytes

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Full text: 1 Database: MEDLINE Main subject: Dendritic Cells / Monocytes / Histone-Lysine N-Methyltransferase / Epigenesis, Genetic / Histocompatibility Antigens Limits: Humans Language: En Year: 2015 Type: Article

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