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The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo.
Karreth, Florian A; Reschke, Markus; Ruocco, Anna; Ng, Christopher; Chapuy, Bjoern; Léopold, Valentine; Sjoberg, Marcela; Keane, Thomas M; Verma, Akanksha; Ala, Ugo; Tay, Yvonne; Wu, David; Seitzer, Nina; Velasco-Herrera, Martin Del Castillo; Bothmer, Anne; Fung, Jacqueline; Langellotto, Fernanda; Rodig, Scott J; Elemento, Olivier; Shipp, Margaret A; Adams, David J; Chiarle, Roberto; Pandolfi, Pier Paolo.
Affiliation
  • Karreth FA; Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Reschke M; Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Ruocco A; Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Ng C; Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Chapuy B; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  • Léopold V; Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Sjoberg M; Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1HH, UK.
  • Keane TM; Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1HH, UK.
  • Verma A; Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10021, USA.
  • Ala U; Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Tay Y; Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Wu D; Meyer Cancer Center, Weill Cornell Medical College, New York, NY 10021, USA.
  • Seitzer N; Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Velasco-Herrera Mdel C; Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1HH, UK.
  • Bothmer A; Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Fung J; Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
  • Langellotto F; Department of Pathology, Children's Hospital and Harvard Medical School, Boston, MA 02115, USA.
  • Rodig SJ; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA.
  • Elemento O; Department of Physiology and Biophysics, Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY 10021, USA.
  • Shipp MA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.
  • Adams DJ; Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1HH, UK.
  • Chiarle R; Department of Pathology, Children's Hospital and Harvard Medical School, Boston, MA 02115, USA; Department of Molecular Biotechnology and Health Sciences, University of Torino, 10124 Torino, Italy.
  • Pandolfi PP; Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA. Electronic address: ppandolf@bidmc.harvard.edu.
Cell ; 161(2): 319-32, 2015 Apr 09.
Article in En | MEDLINE | ID: mdl-25843629
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Full text: 1 Database: MEDLINE Main subject: RNA / Pseudogenes / Lymphoma, Large B-Cell, Diffuse / Proto-Oncogene Proteins B-raf Limits: Animals / Humans Language: En Year: 2015 Type: Article
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Full text: 1 Database: MEDLINE Main subject: RNA / Pseudogenes / Lymphoma, Large B-Cell, Diffuse / Proto-Oncogene Proteins B-raf Limits: Animals / Humans Language: En Year: 2015 Type: Article