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Pharmacokinetic characterization of BMS-936561, an anti-CD70 antibody-drug conjugate, in preclinical animal species and prediction of its pharmacokinetics in humans.
Wang, Haiqing; Rangan, Vangipuram S; Sung, Mei-Chen; Passmore, David; Kempe, Thomas; Wang, Xiaoli; Thevanayagam, Lourdes; Pan, Chin; Rao, Chetana; Srinivasan, Mohan; Zhang, Qian; Gangwar, Sanjeev; Deshpande, Shrikant; Cardarelli, Pina; Marathe, Punit; Yang, Zheng.
Affiliation
  • Wang H; Metabolism and Pharmacokinetics, Bristol-Myers Squibb, Princeton, NJ, United States.
  • Rangan VS; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, CA, United States.
  • Sung MC; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, CA, United States.
  • Passmore D; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, CA, United States.
  • Kempe T; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, CA, United States.
  • Wang X; Clinical Pharmacology, Bristol-Myers Squibb, Princeton, NJ, United States.
  • Thevanayagam L; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, CA, United States.
  • Pan C; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, CA, United States.
  • Rao C; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, CA, United States.
  • Srinivasan M; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, CA, United States.
  • Zhang Q; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, CA, United States.
  • Gangwar S; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, CA, United States.
  • Deshpande S; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, CA, United States.
  • Cardarelli P; Biologics Discovery California, Bristol-Myers Squibb, Redwood City, CA, United States.
  • Marathe P; Metabolism and Pharmacokinetics, Bristol-Myers Squibb, Princeton, NJ, United States.
  • Yang Z; Metabolism and Pharmacokinetics, Bristol-Myers Squibb, Princeton, NJ, United States.
Biopharm Drug Dispos ; 37(2): 93-106, 2016 Mar.
Article in En | MEDLINE | ID: mdl-25869904
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Full text: 1 Database: MEDLINE Main subject: Prodrugs / Immunoconjugates / Antineoplastic Agents, Alkylating / CD27 Ligand / Indoles / Antibodies, Monoclonal Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Year: 2016 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Prodrugs / Immunoconjugates / Antineoplastic Agents, Alkylating / CD27 Ligand / Indoles / Antibodies, Monoclonal Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Year: 2016 Type: Article