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A multi-pronged investigation into the effect of glucose starvation and culture duration on fed-batch CHO cell culture.
Fan, Yuzhou; Jimenez Del Val, Ioscani; Müller, Christian; Lund, Anne Mathilde; Sen, Jette Wagtberg; Rasmussen, Søren Kofoed; Kontoravdi, Cleo; Baycin-Hizal, Deniz; Betenbaugh, Michael J; Weilguny, Dietmar; Andersen, Mikael Rørdam.
Affiliation
  • Fan Y; Network Engineering of Eukaryotic Cell Factories, Department of Systems Biology, Technical University of Denmark, Building 223, 2800 Kgs. Lyngby, Denmark.
  • Jimenez Del Val I; Symphogen A/S, Pederstrupvej, 93, 2750, Ballerup, Denmark.
  • Müller C; Center for Process Systems Engineering, Department of Chemical Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK.
  • Lund AM; Symphogen A/S, Pederstrupvej, 93, 2750, Ballerup, Denmark.
  • Sen JW; Network Engineering of Eukaryotic Cell Factories, Department of Systems Biology, Technical University of Denmark, Building 223, 2800 Kgs. Lyngby, Denmark.
  • Rasmussen SK; Symphogen A/S, Pederstrupvej, 93, 2750, Ballerup, Denmark.
  • Kontoravdi C; Symphogen A/S, Pederstrupvej, 93, 2750, Ballerup, Denmark.
  • Baycin-Hizal D; Center for Process Systems Engineering, Department of Chemical Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK.
  • Betenbaugh MJ; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland 21218.
  • Weilguny D; Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland 21218.
  • Andersen MR; Symphogen A/S, Pederstrupvej, 93, 2750, Ballerup, Denmark. dw@symphogen.com.
Biotechnol Bioeng ; 112(10): 2172-84, 2015 Oct.
Article in En | MEDLINE | ID: mdl-25899530
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Full text: 1 Database: MEDLINE Main subject: Cell Culture Techniques / Culture Media / Glucose Limits: Animals Language: En Year: 2015 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Cell Culture Techniques / Culture Media / Glucose Limits: Animals Language: En Year: 2015 Type: Article