Acute Kidney Injury/drug therapy; Antioxidants/pharmacology; Cacao/chemistry; Chemical and Drug Induced Liver Injury/drug therapy; Phytotherapy; Polyphenols/pharmacology; Acute Kidney Injury/chemically induced; Acute Kidney Injury/genetics; Acute Kidney Injury/metabolism; Animals; Antioxidants/chemistry; Antioxidants/isolation & purification; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury/genetics; Chemical and Drug Induced Liver Injury/metabolism; Chemical and Drug Induced Liver Injury/pathology; Cytochrome P-450 CYP2E1/genetics; Cytochrome P-450 CYP2E1/metabolism; Gene Expression; Glutathione/agonists; Glutathione/metabolism; Glutathione Peroxidase/genetics; Glutathione Peroxidase/metabolism; Injections, Intraperitoneal; Kidney/drug effects; Kidney/metabolism; Kidney/pathology; Lipid Peroxidation/drug effects; Liver/drug effects; Liver/metabolism; Liver/pathology; Male; Malondialdehyde/antagonists & inhibitors; Malondialdehyde/metabolism; Oxidative Stress/drug effects; Phosphatidylcholines/genetics; Phosphatidylcholines/metabolism; Plant Extracts/chemistry; Polyphenols/chemistry; Polyphenols/isolation & purification; RNA, Messenger/genetics; RNA, Messenger/metabolism; Rats; Rats, Inbred F344

cacao polyphenol; carbon tetrachloride; cytochrome P450 2E1(CYP2E1); glutathione peroxidase; lipid peroxide