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Dissecting the genetics of the human transcriptome identifies novel trait-related trans-eQTLs and corroborates the regulatory relevance of non-protein coding loci†.
Kirsten, Holger; Al-Hasani, Hoor; Holdt, Lesca; Gross, Arnd; Beutner, Frank; Krohn, Knut; Horn, Katrin; Ahnert, Peter; Burkhardt, Ralph; Reiche, Kristin; Hackermüller, Jörg; Löffler, Markus; Teupser, Daniel; Thiery, Joachim; Scholz, Markus.
Affiliation
  • Kirsten H; Institute for Medical Informatics, Statistics and Epidemiology, LIFE - Leipzig Research Center for Civilization Diseases, Cognitive Genetics, Department of Cell Therapy.
  • Al-Hasani H; Department for Computer Science, Analysis Strategies Group, Department of Diagnostics, Young Investigators Group Bioinformatics and Transcriptomics, Department Proteomics, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany and.
  • Holdt L; Institute of Laboratory Medicine, Ludwig-Maximilians-University, Munich, Germany.
  • Gross A; Institute for Medical Informatics, Statistics and Epidemiology, LIFE - Leipzig Research Center for Civilization Diseases.
  • Beutner F; LIFE - Leipzig Research Center for Civilization Diseases, Department of Internal Medicine/Cardiology, Heart Center.
  • Krohn K; Interdisciplinary Center for Clinical Research, Faculty of Medicine and .
  • Horn K; Institute for Medical Informatics, Statistics and Epidemiology, LIFE - Leipzig Research Center for Civilization Diseases.
  • Ahnert P; Institute for Medical Informatics, Statistics and Epidemiology, LIFE - Leipzig Research Center for Civilization Diseases.
  • Burkhardt R; LIFE - Leipzig Research Center for Civilization Diseases, Institute of Laboratory Medicine, University of Leipzig, Leipzig, Germany.
  • Reiche K; Department for Computer Science, RNomics Group, Department of Diagnostics, Fraunhofer Institute for Cell Therapy and Immunology- IZI, Leipzig, Germany, Young Investigators Group Bioinformatics and Transcriptomics, Department Proteomics, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Ger
  • Hackermüller J; Department for Computer Science, RNomics Group, Department of Diagnostics, Fraunhofer Institute for Cell Therapy and Immunology- IZI, Leipzig, Germany, Young Investigators Group Bioinformatics and Transcriptomics, Department Proteomics, Helmholtz Centre for Environmental Research - UFZ, Leipzig, Ger
  • Löffler M; Institute for Medical Informatics, Statistics and Epidemiology, LIFE - Leipzig Research Center for Civilization Diseases.
  • Teupser D; Institute of Laboratory Medicine, Ludwig-Maximilians-University, Munich, Germany.
  • Thiery J; LIFE - Leipzig Research Center for Civilization Diseases, Institute of Laboratory Medicine, University of Leipzig, Leipzig, Germany.
  • Scholz M; Institute for Medical Informatics, Statistics and Epidemiology, LIFE - Leipzig Research Center for Civilization Diseases, markus.scholz@imise.uni-leipzig.de.
Hum Mol Genet ; 24(16): 4746-63, 2015 Aug 15.
Article in En | MEDLINE | ID: mdl-26019233
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Full text: 1 Database: MEDLINE Main subject: Leukocytes, Mononuclear / Regulatory Sequences, Nucleic Acid / Gene Expression Regulation / Polymorphism, Single Nucleotide / Quantitative Trait Loci Type of study: Prognostic_studies Limits: Female / Humans / Male Language: En Year: 2015 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Leukocytes, Mononuclear / Regulatory Sequences, Nucleic Acid / Gene Expression Regulation / Polymorphism, Single Nucleotide / Quantitative Trait Loci Type of study: Prognostic_studies Limits: Female / Humans / Male Language: En Year: 2015 Type: Article