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The role of HPV RNA transcription, immune response-related gene expression and disruptive TP53 mutations in diagnostic and prognostic profiling of head and neck cancer.
Wichmann, Gunnar; Rosolowski, Maciej; Krohn, Knut; Kreuz, Markus; Boehm, Andreas; Reiche, Anett; Scharrer, Ulrike; Halama, Dirk; Bertolini, Julia; Bauer, Ulrike; Holzinger, Dana; Pawlita, Michael; Hess, Jochen; Engel, Christoph; Hasenclever, Dirk; Scholz, Markus; Ahnert, Peter; Kirsten, Holger; Hemprich, Alexander; Wittekind, Christian; Herbarth, Olf; Horn, Friedemann; Dietz, Andreas; Loeffler, Markus.
Affiliation
  • Wichmann G; Clinic for Otorhinolaryngology, University Hospital Leipzig, Liebigstr. 10-14, 04103, Leipzig, Germany.
  • Rosolowski M; LIFE-Leipzig Research Center for Civilization Diseases, University of Leipzig, 04103, Leipzig, Germany.
  • Krohn K; LIFE-Leipzig Research Center for Civilization Diseases, University of Leipzig, 04103, Leipzig, Germany.
  • Kreuz M; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, 04107, Leipzig, Germany.
  • Boehm A; Faculty of Medicine, Interdisciplinary Center for Clinical Research, University of Leipzig, 04103, Leipzig, Germany.
  • Reiche A; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, 04107, Leipzig, Germany.
  • Scharrer U; Clinic for Otorhinolaryngology, University Hospital Leipzig, Liebigstr. 10-14, 04103, Leipzig, Germany.
  • Halama D; Clinic for Otorhinolaryngology, University Hospital Leipzig, Liebigstr. 10-14, 04103, Leipzig, Germany.
  • Bertolini J; Clinic for Otorhinolaryngology, University Hospital Leipzig, Liebigstr. 10-14, 04103, Leipzig, Germany.
  • Bauer U; LIFE-Leipzig Research Center for Civilization Diseases, University of Leipzig, 04103, Leipzig, Germany.
  • Holzinger D; Clinic for Maxillofacial Surgery, University Hospital Leipzig, 04103, Leipzig, Germany.
  • Pawlita M; Institute of Pathology, University Hospital Leipzig, 04103, Leipzig, Germany.
  • Hess J; Institute of Pathology, University Hospital Leipzig, 04103, Leipzig, Germany.
  • Engel C; Division of Genome Modifications and Carcinogenesis (F020), Infection and Cancer Program, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69121, Heidelberg, Germany.
  • Hasenclever D; Division of Genome Modifications and Carcinogenesis (F020), Infection and Cancer Program, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69121, Heidelberg, Germany.
  • Scholz M; Research Group Molecular Mechanisms of Head and Neck Tumors, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Ahnert P; Section Experimental and Translational Head and Neck Oncology, Department of Otolaryngology, Head and Neck Surgery University Heidelberg, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
  • Kirsten H; LIFE-Leipzig Research Center for Civilization Diseases, University of Leipzig, 04103, Leipzig, Germany.
  • Hemprich A; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, 04107, Leipzig, Germany.
  • Wittekind C; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, 04107, Leipzig, Germany.
  • Herbarth O; LIFE-Leipzig Research Center for Civilization Diseases, University of Leipzig, 04103, Leipzig, Germany.
  • Horn F; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, 04107, Leipzig, Germany.
  • Dietz A; LIFE-Leipzig Research Center for Civilization Diseases, University of Leipzig, 04103, Leipzig, Germany.
  • Loeffler M; Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, 04107, Leipzig, Germany.
Int J Cancer ; 137(12): 2846-57, 2015 Dec 15.
Article in En | MEDLINE | ID: mdl-26095926
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Full text: 1 Database: MEDLINE Main subject: RNA, Viral / Carcinoma, Squamous Cell / Tumor Suppressor Protein p53 / Papillomavirus Infections / Human papillomavirus 16 / Head and Neck Neoplasms Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies Limits: Humans Language: En Year: 2015 Type: Article
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Full text: 1 Database: MEDLINE Main subject: RNA, Viral / Carcinoma, Squamous Cell / Tumor Suppressor Protein p53 / Papillomavirus Infections / Human papillomavirus 16 / Head and Neck Neoplasms Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies Limits: Humans Language: En Year: 2015 Type: Article