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NUMB phosphorylation destabilizes p53 and promotes self-renewal of tumor-initiating cells by a NANOG-dependent mechanism in liver cancer.
Siddique, Hifzur R; Feldman, Douglas E; Chen, Chia-Lin; Punj, Vasu; Tokumitsu, Hiroshi; Machida, Keigo.
Affiliation
  • Siddique HR; Department of Molecular Microbiology and Immunology, University of Southern California, Keck School of Medicine, Los Angeles, CA.
  • Feldman DE; Department of Molecular Microbiology and Immunology, University of Southern California, Keck School of Medicine, Los Angeles, CA.
  • Chen CL; Department of Molecular Microbiology and Immunology, University of Southern California, Keck School of Medicine, Los Angeles, CA.
  • Punj V; Norris Comprehensive Cancer Center, University of Southern California, Keck School of Medicine, Los Angeles, CA.
  • Tokumitsu H; Division of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama University, Okayama 700-8530, Japan.
  • Machida K; Department of Molecular Microbiology and Immunology, University of Southern California, Keck School of Medicine, Los Angeles, CA.
Hepatology ; 62(5): 1466-79, 2015 Nov.
Article in En | MEDLINE | ID: mdl-26174965
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Full text: 1 Database: MEDLINE Main subject: Neoplastic Stem Cells / Tumor Suppressor Protein p53 / Homeodomain Proteins / Liver Neoplasms / Membrane Proteins / Nerve Tissue Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2015 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Neoplastic Stem Cells / Tumor Suppressor Protein p53 / Homeodomain Proteins / Liver Neoplasms / Membrane Proteins / Nerve Tissue Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Year: 2015 Type: Article