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High-Dose Chemotherapy and Autologous Stem Cell Transplant in Older Patients with Lymphoma.
Lahoud, Oscar B; Sauter, Craig S; Hamlin, Paul A; Dahi, Parastoo Bahrami.
Affiliation
  • Lahoud OB; Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Curr Oncol Rep ; 17(9): 42, 2015 Sep.
Article in En | MEDLINE | ID: mdl-26201264
ABSTRACT
High-dose chemotherapy followed by autologous hematopoietic stem cell transplant (HDT/ASCT) can improve survival in patients with lymphoma. Limited experience is available on the safety and efficacy of HDT/ASCT in elderly patients. In this article, we review the published data on the role of HDT/ASCT in management of lymphoma in older patients. Based on available data, evaluation of comorbidities, functional status, and comprehensive geriatric assessment (CGA) will help identify those who can benefit most from this intervention. Prospective clinical trials focusing on HDT/ASCT in older patients with lymphoma are needed to establish optimal management protocols in this select population.
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Full text: 1 Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Hematopoietic Stem Cell Transplantation / Lymphoma Type of study: Diagnostic_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Year: 2015 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Antineoplastic Combined Chemotherapy Protocols / Hematopoietic Stem Cell Transplantation / Lymphoma Type of study: Diagnostic_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Year: 2015 Type: Article