Alcohol Selectivity in a Synthetic Thermophilic n-Butanol Pathway Is Driven by Biocatalytic and Thermostability Characteristics of Constituent Enzymes.

Loder, Andrew J; Zeldes, Benjamin M; Garrison, G Dale; Lipscomb, Gina L; Adams, Michael W W; Kelly, Robert M

Loder, Andrew J; Zeldes, Benjamin M; Garrison, G Dale; Lipscomb, Gina L; Adams, Michael W W; Kelly, Robert M.

Affiliation

Loder AJ; Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA.
Zeldes BM; Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA.
Garrison GD; Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA.
Lipscomb GL; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Adams MW; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Kelly RM; Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA rmkelly@ncsu.edu.

Appl Environ Microbiol ; 81(20): 7187-200, 2015 Oct.

Article in En | MEDLINE | ID: mdl-26253677

Subject(s)

1-Butanol/metabolism; Acetyl-CoA C-Acyltransferase/metabolism; Acyl Coenzyme A/metabolism; Alcohol Dehydrogenase/metabolism; Alcohol Oxidoreductases/metabolism; Aldehyde Oxidoreductases/metabolism; Biocatalysis; Chromatography, Gas; Clostridium acetobutylicum/metabolism; Clostridium thermocellum/metabolism; Thermoanaerobacter/metabolism

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Full text: 1 Database: MEDLINE Main subject: 1-Butanol Type of study: Prognostic_studies Language: En Year: 2015 Type: Article

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Full text: 1 Database: MEDLINE Main subject: 1-Butanol Type of study: Prognostic_studies Language: En Year: 2015 Type: Article