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Polyketides from mantis-associated fungus Daldinia eschscholzii IFB-TL01.
Wang, Gang; Fan, Jing-Yang; Zhang, Wen-Jing; Hua, Cheng-Pin; Chen, Chao-Jun; Yan, Wei; Ge, Hui-Ming; Jiao, Rui-Hua; Tan, Ren-Xiang.
Affiliation
  • Wang G; Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201).
  • Fan JY; Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201).
  • Zhang WJ; Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201).
  • Hua CP; Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201).
  • Chen CJ; Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201).
  • Yan W; Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201).
  • Ge HM; Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201).
  • Jiao RH; Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201). rhjiao@nju.edu.cn.
  • Tan RX; Institute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China (phone/fax: +86-25-83593201).
Chem Biodivers ; 12(9): 1349-55, 2015 Sep.
Article in En | MEDLINE | ID: mdl-26363879
ABSTRACT
Three new polyketides, named daldinone F (1), nodulisporin G (2), and dalmanol C (3), together with five known compounds, 4-8, were isolated from cultures of Daldinia eschscholzii. The structures of the new compounds were elucidated by extensive NMR and MS analyses. Compound 1 showed moderate cytotoxic activity against SW480 cancer cells with an IC50 value of 9.59 µM, and its absolute configuration was determined by single crystal X-ray diffraction.
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Full text: 1 Database: MEDLINE Main subject: Xylariales / Polyketides Type of study: Risk_factors_studies Language: En Year: 2015 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Xylariales / Polyketides Type of study: Risk_factors_studies Language: En Year: 2015 Type: Article