Development of Trypsin-Like Serine Protease Inhibitors as Therapeutic Agents: Opportunities, Challenges, and their Unique Structure-Based Rationales.

Liang, Guyan; Bowen, J Phillip

Liang, Guyan; Bowen, J Phillip.

Affiliation

Liang G; Budd Larner PC, 150 John F. Kennedy Pkwy, Short Hills, NJ 07078. Guyan.Liang@outlook.com.

Curr Top Med Chem ; 16(13): 1506-29, 2016.

Article in En | MEDLINE | ID: mdl-26369819

Subject(s)

Anticoagulants/chemistry; Anticoagulants/therapeutic use; Serine Endopeptidases/metabolism; Serine Proteinase Inhibitors/pharmacology; Serine Proteinase Inhibitors/therapeutic use; Administration, Oral; Anticoagulants/administration & dosage; Anticoagulants/pharmacology; Blood Coagulation/drug effects; Humans; Serine Proteinase Inhibitors/chemical synthesis; Serine Proteinase Inhibitors/chemistry; Structure-Activity Relationship

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Database: MEDLINE Main subject: Serine Endopeptidases / Serine Proteinase Inhibitors / Anticoagulants Limits: Humans Language: En Year: 2016 Type: Article

Search on Google

XML

PubMed Links

Database: MEDLINE Main subject: Serine Endopeptidases / Serine Proteinase Inhibitors / Anticoagulants Limits: Humans Language: En Year: 2016 Type: Article