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CARD9 mutation linked to Corynespora cassiicola infection in a Chinese patient.
Yan, X X; Yu, C P; Fu, X A; Bao, F F; Du, D H; Wang, C; Wang, N; Wang, S F; Shi, Z X; Zhou, G Z; Tian, H Q; Liu, H; Zhang, F R.
Affiliation
  • Yan XX; Shandong Clinical College of Skin Diseases, Anhui Medical University, Jinan, Shandong, China.
  • Yu CP; Shandong Provincial Hospital for Skin Diseases, Shandong University, Jinan, Shandong, China.
  • Fu XA; Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, 27397 Jingshi Road, Jinan, Shandong, 250022, China.
  • Bao FF; Shandong Provincial Hospital for Skin Diseases, Shandong University, Jinan, Shandong, China.
  • Du DH; Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, 27397 Jingshi Road, Jinan, Shandong, 250022, China.
  • Wang C; Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, 27397 Jingshi Road, Jinan, Shandong, 250022, China.
  • Wang N; Shandong Provincial Key Lab for Dermatovenereology, Jinan, Shandong, China.
  • Wang SF; Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, 27397 Jingshi Road, Jinan, Shandong, 250022, China.
  • Shi ZX; Shandong Provincial Key Lab for Dermatovenereology, Jinan, Shandong, China.
  • Zhou GZ; Shandong Provincial Hospital for Skin Diseases, Shandong University, Jinan, Shandong, China.
  • Tian HQ; Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, 27397 Jingshi Road, Jinan, Shandong, 250022, China.
  • Liu H; Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, 27397 Jingshi Road, Jinan, Shandong, 250022, China.
  • Zhang FR; Shandong Provincial Key Lab for Dermatovenereology, Jinan, Shandong, China.
Br J Dermatol ; 174(1): 176-9, 2016 Jan.
Article in En | MEDLINE | ID: mdl-26440558
ABSTRACT
Corynespora cassiicola is a plant pathogen associated with leaf-spotting disease. The fungus has been found on diverse substrates leaves, stems and roots of plants; nematode cysts and human skin. It rarely causes human infections. Here we report one case of subcutaneous phaeohyphomycosis caused by C. cassiicola with prominent tissue necrosis in a woman. All of her clinical features pointed towards a genetic linkage. Hence, whole-exome sequencing and Sanger sequencing were performed on this patient. One mutation of CARD9 was detected.
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Full text: 1 Database: MEDLINE Main subject: Ascomycota / Dermatomycoses / CARD Signaling Adaptor Proteins / Facial Dermatoses / Mutation Limits: Adult / Female / Humans Language: En Year: 2016 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Ascomycota / Dermatomycoses / CARD Signaling Adaptor Proteins / Facial Dermatoses / Mutation Limits: Adult / Female / Humans Language: En Year: 2016 Type: Article