Budesonide Inhibits Intracellular Infection with Non-Typeable Haemophilus influenzae Despite Its Anti-Inflammatory Effects in Respiratory Cells and Human Lung Tissue: A Role for p38 MAP Kinase.

Wagner, Christopher; Goldmann, Torsten; Rohmann, Kristina; Rupp, Jan; Marwitz, Sebastian; Rotta Detto Loria, Johannes; Limmer, Stefan; Zabel, Peter; Dalhoff, Klaus; Drömann, Daniel

Wagner, Christopher; Goldmann, Torsten; Rohmann, Kristina; Rupp, Jan; Marwitz, Sebastian; Rotta Detto Loria, Johannes; Limmer, Stefan; Zabel, Peter; Dalhoff, Klaus; Drömann, Daniel.

Affiliation

Wagner C; Medical Clinic III, University of Schleswig-Holstein, Lx00FC;beck, Germany.

Respiration ; 90(5): 416-25, 2015.

Article in En | MEDLINE | ID: mdl-26452008

Subject(s)

Budesonide/pharmacology; Haemophilus influenzae/drug effects; Pulmonary Disease, Chronic Obstructive/drug therapy; p38 Mitogen-Activated Protein Kinases/metabolism; Administration, Inhalation; Anti-Inflammatory Agents/pharmacology; Blotting, Western; Budesonide/adverse effects; Cells, Cultured; Culture Media, Conditioned; Enzyme Induction/drug effects; Enzyme-Linked Immunosorbent Assay; Epithelial Cells/drug effects; Haemophilus Infections/etiology; Haemophilus Infections/physiopathology; Humans; Immunohistochemistry; Polymerase Chain Reaction; Pulmonary Disease, Chronic Obstructive/microbiology; Sensitivity and Specificity; p38 Mitogen-Activated Protein Kinases/drug effects

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Full text: 1 Database: MEDLINE Main subject: Haemophilus influenzae / Budesonide / Pulmonary Disease, Chronic Obstructive / P38 Mitogen-Activated Protein Kinases Type of study: Diagnostic_studies / Etiology_studies Limits: Humans Language: En Year: 2015 Type: Article

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