Protein Arginine Methyltransferase 6 (Prmt6) Is Essential for Early Zebrafish Development through the Direct Suppression of gadd45&#945;a Stress Sensor Gene.

Zhao, Xin-Xi; Zhang, Yun-Bin; Ni, Pei-Li; Wu, Zhi-Li; Yan, Yuan-Chang; Li, Yi-Ping

Protein Arginine Methyltransferase 6 (Prmt6) Is Essential for Early Zebrafish Development through the Direct Suppression of gadd45αa Stress Sensor Gene.

Zhao, Xin-Xi; Zhang, Yun-Bin; Ni, Pei-Li; Wu, Zhi-Li; Yan, Yuan-Chang; Li, Yi-Ping.

Affiliation

Zhao XX; From the State Key Laboratory of Cell Biology, Shanghai Key Laboratory for Molecular Andrology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Zhang YB; From the State Key Laboratory of Cell Biology, Shanghai Key Laboratory for Molecular Andrology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Ni PL; From the State Key Laboratory of Cell Biology, Shanghai Key Laboratory for Molecular Andrology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Wu ZL; From the State Key Laboratory of Cell Biology, Shanghai Key Laboratory for Molecular Andrology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Yan YC; From the State Key Laboratory of Cell Biology, Shanghai Key Laboratory for Molecular Andrology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
Li YP; From the State Key Laboratory of Cell Biology, Shanghai Key Laboratory for Molecular Andrology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China Yipingli@sibcb.ac.cn.

J Biol Chem ; 291(1): 402-12, 2016 Jan 01.

Article in En | MEDLINE | ID: mdl-26487724

Subject(s)

Cell Cycle Proteins/genetics; Embryonic Development; Nuclear Proteins/genetics; Protein-Arginine N-Methyltransferases/genetics; Zebrafish Proteins/genetics; Zebrafish/embryology; Zebrafish/genetics; Animals; Apoptosis/drug effects; Cell Cycle Proteins/metabolism; Embryonic Development/drug effects; Embryonic Development/genetics; JNK Mitogen-Activated Protein Kinases/metabolism; Morpholinos/pharmacology; Nuclear Proteins/metabolism; Protein-Arginine N-Methyltransferases/metabolism; RNA, Messenger/genetics; RNA, Messenger/metabolism; Stress, Physiological/drug effects; Stress, Physiological/genetics; Up-Regulation/drug effects; Zebrafish Proteins/metabolism; p38 Mitogen-Activated Protein Kinases/metabolism

Key words

apoptosis; c-Jun N-terminal kinase (JNK); gadd45αa; histone methylation; p38; prmt6; zebrafish

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Full text: 1 Database: MEDLINE Main subject: Protein-Arginine N-Methyltransferases / Zebrafish / Nuclear Proteins / Cell Cycle Proteins / Zebrafish Proteins / Embryonic Development Type of study: Prognostic_studies Limits: Animals Language: En Year: 2016 Type: Article

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