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Enhancing SHP-1 expression with 5-azacytidine may inhibit STAT3 activation and confer sensitivity in lestaurtinib (CEP-701)-resistant FLT3-ITD positive acute myeloid leukemia.
Al-Jamal, Hamid Ali Nagi; Mat Jusoh, Siti Asmaa; Hassan, Rosline; Johan, Muhammad Farid.
Affiliation
  • Al-Jamal HA; Department of Haematology, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. aljamalhamid08@gmail.com.
  • Mat Jusoh SA; Department of Haematology, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. asma_sof88@yahoo.com.
  • Hassan R; Department of Haematology, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. roslin@usm.my.
  • Johan MF; Department of Haematology, School of Medical Sciences, Universiti Sains Malaysia, 16150, Kubang Kerian, Kelantan, Malaysia. faridjohan@usm.my.
BMC Cancer ; 15: 869, 2015 Nov 07.
Article in En | MEDLINE | ID: mdl-26547689
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Full text: 1 Database: MEDLINE Main subject: Azacitidine / Leukemia, Myeloid, Acute / Gene Expression Regulation, Leukemic / Gene Duplication / Fms-Like Tyrosine Kinase 3 / STAT3 Transcription Factor / Protein Tyrosine Phosphatase, Non-Receptor Type 6 Type of study: Diagnostic_studies Limits: Humans Language: En Year: 2015 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Azacitidine / Leukemia, Myeloid, Acute / Gene Expression Regulation, Leukemic / Gene Duplication / Fms-Like Tyrosine Kinase 3 / STAT3 Transcription Factor / Protein Tyrosine Phosphatase, Non-Receptor Type 6 Type of study: Diagnostic_studies Limits: Humans Language: En Year: 2015 Type: Article