Controlled synthesis of N,N,N-trimethyl chitosan for modulated bioadhesion and nasal membrane permeability.

Pardeshi, Chandrakantsing V; Belgamwar, Veena S

Pardeshi, Chandrakantsing V; Belgamwar, Veena S.

Affiliation

Pardeshi CV; Industrial Pharmacy Laboratory, Department of Pharmaceutics, R. C. Patel Institute of Pharmaceutical Education and Research, Shirpur, Maharashtra, India. Electronic address: chandrakantpardeshi11@gmail.com.
Belgamwar VS; Department of Pharmaceutical Sciences, RTM Nagpur University, Nagpur, Maharashtra, India. Electronic address: vbelgamwar@gmail.com.

Int J Biol Macromol ; 82: 933-44, 2016 Jan.

Article in En | MEDLINE | ID: mdl-26562548

Subject(s)

Cell Membrane Permeability/drug effects; Chitosan/chemistry; Chitosan/pharmacology; Nasal Mucosa/drug effects; Nasal Mucosa/metabolism; Biopolymers/chemistry; Chitosan/chemical synthesis; Materials Testing; Molecular Weight; Nanoparticles/chemistry; Nanoparticles/ultrastructure; Proton Magnetic Resonance Spectroscopy; Rheology; Solubility; Thermodynamics

Key words

Chitosan; Methyl iodide (PubChem CID: 6328); Mucoadhesion; N,N,N-Trimethyl chitosan; N-Methyl-2-pyrrolidinone (PubChem CID: 13387); Nanoparticles; Nasal delivery; Polysaccharides; Reductive methylation; Sodium iodide (PubChem CID: 5238)

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Full text: 1 Database: MEDLINE Main subject: Cell Membrane Permeability / Chitosan / Nasal Mucosa Language: En Year: 2016 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Cell Membrane Permeability / Chitosan / Nasal Mucosa Language: En Year: 2016 Type: Article