Chromosomal instability in mammalian pre-implantation embryos: potential causes, detection methods, and clinical consequences.

Daughtry, Brittany L; Chavez, Shawn L

Daughtry, Brittany L; Chavez, Shawn L.

Affiliation

Daughtry BL; Department of Cell, Developmental & Cancer Biology, Graduate Program in Molecular & Cellular Biosciences, Oregon Health & Science University School of Medicine, Portland, Ore., USA.
Chavez SL; Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, 505 NW 185th Avenue, Beaverton, OR 97006, USA.

Cell Tissue Res ; 363(1): 201-225, 2016 Jan.

Article in En | MEDLINE | ID: mdl-26590822

Subject(s)

Aneuploidy; Chromosomal Instability; Preimplantation Diagnosis/methods; Animals; Embryo, Mammalian/metabolism; Embryo, Mammalian/pathology; Embryo, Mammalian/ultrastructure; Genomics/methods; Humans; In Situ Hybridization, Fluorescence/methods; Meiosis; Microarray Analysis/methods; Mitosis; Real-Time Polymerase Chain Reaction/methods; Time-Lapse Imaging/methods

Key words

Aneuploidy; Chromothripsis; Fragmentation; Micronuclei; Pre-implantation embryo

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Full text: 1 Database: MEDLINE Main subject: Preimplantation Diagnosis / Chromosomal Instability / Aneuploidy Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies Limits: Animals / Humans Language: En Year: 2016 Type: Article

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