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Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota.
Forslund, Kristoffer; Hildebrand, Falk; Nielsen, Trine; Falony, Gwen; Le Chatelier, Emmanuelle; Sunagawa, Shinichi; Prifti, Edi; Vieira-Silva, Sara; Gudmundsdottir, Valborg; Pedersen, Helle K; Arumugam, Manimozhiyan; Kristiansen, Karsten; Voigt, Anita Yvonne; Vestergaard, Henrik; Hercog, Rajna; Costea, Paul Igor; Kultima, Jens Roat; Li, Junhua; Jørgensen, Torben; Levenez, Florence; Dore, Joël; Nielsen, H Bjørn; Brunak, Søren; Raes, Jeroen; Hansen, Torben; Wang, Jun; Ehrlich, S Dusko; Bork, Peer; Pedersen, Oluf.
Affiliation
  • Forslund K; European Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.
  • Hildebrand F; European Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.
  • Nielsen T; Center for the Biology of Disease, VIB, Leuven, Belgium.
  • Falony G; Department of Bioscience Engineering, Vrije Universiteit Brussel, Brussels, Belgium.
  • Le Chatelier E; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Sunagawa S; Center for the Biology of Disease, VIB, Leuven, Belgium.
  • Prifti E; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Molecular Bacteriology, Leuven, Belgium.
  • Vieira-Silva S; MICALIS, Institut National de la Recherche Agronomique, Jouy en Josas, France.
  • Gudmundsdottir V; Metagenopolis, Institut National de la Recherche Agronomique, Jouy en Josas, France.
  • Pedersen HK; European Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.
  • Arumugam M; MICALIS, Institut National de la Recherche Agronomique, Jouy en Josas, France.
  • Kristiansen K; Metagenopolis, Institut National de la Recherche Agronomique, Jouy en Josas, France.
  • Voigt AY; Institute of Cardiometabolism and Nutrition, Paris, France.
  • Vestergaard H; Center for the Biology of Disease, VIB, Leuven, Belgium.
  • Hercog R; KU Leuven - University of Leuven, Department of Microbiology and Immunology, Rega Institute for Medical Research, Laboratory of Molecular Bacteriology, Leuven, Belgium.
  • Costea PI; Center for Biological Sequence Analysis, Dept. of Systems Biology, Technical University of Denmark, Kongens Lyngby, Denmark.
  • Kultima JR; Center for Biological Sequence Analysis, Dept. of Systems Biology, Technical University of Denmark, Kongens Lyngby, Denmark.
  • Li J; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Jørgensen T; Department of Biology, University of Copenhagen, Copenhagen, Denmark.
  • Levenez F; European Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.
  • Dore J; Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
  • Nielsen HB; The Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Brunak S; European Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.
  • Raes J; European Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.
  • Hansen T; European Molecular Biology Laboratory, Structural and Computational Biology Unit, Heidelberg, Germany.
  • Wang J; BGI-Shenzhen, Shenzhen, China.
  • Ehrlich SD; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark.
  • Bork P; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Pedersen O; Faculty of Medicine, University of Aalborg, Aalborg, Denmark.
Nature ; 528(7581): 262-266, 2015 Dec 10.
Article in En | MEDLINE | ID: mdl-26633628
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Full text: 1 Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 / Gastrointestinal Microbiome / Metformin Limits: Female / Humans / Male Language: En Year: 2015 Type: Article
Fulltext
Print
XML
PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 / Gastrointestinal Microbiome / Metformin Limits: Female / Humans / Male Language: En Year: 2015 Type: Article