Early-life stress changes expression of GnRH and kisspeptin genes and DNA methylation of GnRH3 promoter in the adult zebrafish brain.

Khor, Yee Min; Soga, Tomoko; Parhar, Ishwar S

Khor, Yee Min; Soga, Tomoko; Parhar, Ishwar S.

Affiliation

Khor YM; Brain Research Institute, School of Medicine and Health Sciences, Monash University, Malaysia.
Soga T; Brain Research Institute, School of Medicine and Health Sciences, Monash University, Malaysia. Electronic address: tomoko.soga@monash.edu.
Parhar IS; Brain Research Institute, School of Medicine and Health Sciences, Monash University, Malaysia.

Gen Comp Endocrinol ; 227: 84-93, 2016 Feb 01.

Article in En | MEDLINE | ID: mdl-26686318

Subject(s)

Brain/metabolism; DNA Methylation; Gonadotropin-Releasing Hormone/genetics; Kisspeptins/genetics; Promoter Regions, Genetic; Pyrrolidonecarboxylic Acid/analogs & derivatives; Stress, Psychological/genetics; Zebrafish/genetics; Animals; Gonadotropin-Releasing Hormone/metabolism; Gonads/metabolism; Kisspeptins/metabolism; Male; Pyrrolidonecarboxylic Acid/metabolism; Reproduction; Stress, Psychological/metabolism; Zebrafish/metabolism; Zebrafish Proteins/metabolism

Key words

Dexamethasone; Epigenetics; HPG; Hypothalamus; Preoptic area; Reproduction

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Full text: 1 Database: MEDLINE Main subject: Pyrrolidonecarboxylic Acid / Stress, Psychological / Zebrafish / Brain / Gonadotropin-Releasing Hormone / Promoter Regions, Genetic / DNA Methylation / Kisspeptins Limits: Animals Language: En Year: 2016 Type: Article

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