Seom guidelines for the treatment of gastric cancer 2015.
Clin Transl Oncol
; 17(12): 996-1004, 2015 Dec.
Article
in En
| MEDLINE
| ID: mdl-26691658
ABSTRACT
Gastric cancer is the fourth cause of death by cancer in Spain and a significant medical problem. Molecular biology results evidence that gastroesophageal junction tumors and gastric cancer should be considered as two independent entities with a different prognosis and treatment approach. Endoscopic resection in very early tumors is feasible. Neoadjuvant and adjuvant therapy in locally advanced resectable tumor increase overall survival and should be considered standard treatments. In stage IV tumors, platinum-fluoropyrimidine-based schedule, with trastuzumab in HER2-overexpressed tumors, is the first-line treatment. Different therapies in second line have demonstrated in randomized studies their clear benefit in survival improvement.
Key words
Full text:
1
Database:
MEDLINE
Main subject:
Stomach Neoplasms
/
Practice Guidelines as Topic
Type of study:
Clinical_trials
/
Diagnostic_studies
/
Guideline
/
Prognostic_studies
/
Screening_studies
Limits:
Humans
Language:
En
Year:
2015
Type:
Article