Adverse effects of long-term administration of fluvoxamine on haematology, blood biochemistry and fertility in male albino rats: a possible effect of cessation.

Galal, A A A; Alam, R T M; Abd El-Aziz, R M

Galal, A A A; Alam, R T M; Abd El-Aziz, R M.

Affiliation

Galal AA; Department of Pharmacology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt. azzapharma@yahoo.com.
Alam RT; Department of Clinical Pathology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.
Abd El-Aziz RM; Department of Physiology, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt.

Andrologia ; 48(9): 914-922, 2016 Nov.

Article in En | MEDLINE | ID: mdl-26771175

Subject(s)

Fertility/drug effects; Fluvoxamine/adverse effects; Selective Serotonin Reuptake Inhibitors/adverse effects; Administration, Oral; Alanine Transaminase/blood; Animals; Blood Chemical Analysis; DNA Fragmentation; Dose-Response Relationship, Drug; Fluvoxamine/administration & dosage; Gonadal Steroid Hormones/blood; Leukocytosis/chemically induced; Male; Oxidative Stress/drug effects; Rats; Selective Serotonin Reuptake Inhibitors/administration & dosage; Spermatozoa/drug effects; Testis/drug effects; Testis/metabolism; Testis/pathology

Key words

Blood biochemistry; fertility; fluvoxamine; haematology; recovery

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Full text: 1 Database: MEDLINE Main subject: Fluvoxamine / Selective Serotonin Reuptake Inhibitors / Fertility Limits: Animals Language: En Year: 2016 Type: Article

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Full text: 1 Database: MEDLINE Main subject: Fluvoxamine / Selective Serotonin Reuptake Inhibitors / Fertility Limits: Animals Language: En Year: 2016 Type: Article